HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: RGPA1 (Q6GYQ0)
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)
Gene: RALGAPA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 2036
+	Hs
		909678 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		927396 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91
+	Hs
		927156 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RPGP2_HUMAN (1630-2013): 1.11e-114: 384: 19.90
+	Hs
		909669 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RPGP2_HUMAN (1630-2013): 1.11e-114: 384: 19.90
+	Hs
		196429 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SI1L1_HUMAN (1683-2015): 2.28e-106: 380: 19.22
+	Hs
		927611 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SI1L2_HUMAN (1694-2016): 4.06e-106: 379: 18.88
+	Hs
		196427 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SI1L1_HUMAN (1683-2015): 2.28e-106: 380: 19.22
+	Hs
		910116 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SI1L2_HUMAN (1694-2016): 4.06e-106: 379: 18.88
+	Hs
		927256 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		909769 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		230235 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Hs
		230231 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Hs
		835039 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TSC2_HUMAN (1727-2033): 1.18e-96: 349: 23.90
+	Hs
		835035 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TSC2_HUMAN (1727-2033): 1.18e-96: 349: 23.90
+	Hs
		812876 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		RPGP1_HUMAN (1627-2013): 3.28e-93: 319: 18.30
+	Hs
		812874 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RPGP1_HUMAN (1627-2013): 3.28e-93: 319: 18.30
+	Dm
		114591 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		M9PD17_DROME (1750-2010): 4.88e-74: 277: 25.18
+	Dm
		114606 1433E_DROME (2-242): 3.33e-143: 402: 66.67		M9PD17_DROME (1750-2010): 4.88e-74: 277: 25.18
+	Dm
		664663 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		Q9VW83_DROME (1750-2010): 5.15e-74: 277: 25.18
+	Mm
		926787 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q3TQ10_MOUSE (1840-2034): 1.27e-76: 256: 22.17