HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: R3HD1 (Q15032)
R3H domain-containing protein 1
Gene: R3HDM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.620

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 1099
+	Hs
		927620 ATX1_HUMAN (1-815): 0: 1349: 100.00		R3HD2_HUMAN (482-1099): 2.59e-38: 157: 42.11
+	Mm
		107058 ATX1_MOUSE (1-815): 0: 1271: 86.89		F8VPR5_MOUSE (391-939): 1.42e-55: 214: 15.67
+	Hs
		927454 ATX1_HUMAN (1-815): 0: 1349: 100.00		ATX2L_HUMAN (243-679): 1.15e-10: 68.3: 9.38
+	Hs
		927463 ATX1_HUMAN (1-815): 0: 1349: 100.00		CBP_HUMAN (515-920): 1.33e-09: 64.8: 12.65
+	Mm
		927858 ATX1_MOUSE (1-815): 0: 1271: 86.89		ATX2L_MOUSE (404-1088): 3.18e-11: 69.8: 10.07
+	Mm
		927827 ATX1_MOUSE (1-815): 0: 1271: 86.89		IF4G1_MOUSE (389-927): 1.94e-10: 67.5: 10.84
+	Mm
		927758 ATX1_MOUSE (1-815): 0: 1271: 86.89		SC31A_MOUSE (530-868): 7.44e-10: 65.5: 12.36