HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: ESYT1 (Q9BSJ8)
Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)
Gene: ESYT1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	35271311, 15161933
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1104
+	Hs
		909970 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		683675 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		905058 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Mm
		926842 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		Q8C8C0_MOUSE (799-1102): 4.26e-35: 145: 16.77
+	Hs
		135776 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		P3C2B_HUMAN (948-1095): 4.64e-14: 79.3: 37.50
+	Hs
		135774 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		P3C2B_HUMAN (948-1095): 4.64e-14: 79.3: 37.50
+	Dm
		664613 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		Q7K3H0_DROME (922-1095): 2.72e-14: 80.1: 33.52
+	Hs
		135766 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		P3C2B_HUMAN (948-1095): 4.64e-14: 79.3: 37.50
+	Hs
		135769 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		P3C2B_HUMAN (948-1095): 4.64e-14: 79.3: 37.50
+	Hs
		48275 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		128838 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		P3C2A_HUMAN (973-1095): 9.86e-10: 65.1: 35.48
+	Mm
		910341 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		RIMS2_MOUSE (973-1095): 3.57e-10: 66.6: 32.54
+	Hs
		128836 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		P3C2A_HUMAN (973-1095): 9.86e-10: 65.1: 35.48
+	Hs
		128810 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		P3C2A_HUMAN (973-1095): 9.86e-10: 65.1: 35.48
+	Hs
		128813 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		P3C2A_HUMAN (973-1095): 9.86e-10: 65.1: 35.48
+	Rn
		812782 1433F_RAT (2-240): 1.16e-107: 312: 74.07		RP3A_RAT (311-443): 3.58e-21: 101: 16.20
+	Hs
		135773 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		P3C2B_HUMAN (948-1095): 4.64e-14: 79.3: 37.50
+	Hs
		48316 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		48340 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		128834 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		P3C2A_HUMAN (973-1095): 9.86e-10: 65.1: 35.48