HitPredict

Interactor 1: RSMN (P63162)
Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein)
Gene: SNRPN

Interactor 2: U1SBP (Q16560)
U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog)
Gene: SNRNP35

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005654 - nucleoplasm GO:0008380 - RNA splicing
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 240 Hs			1 246
+	Hs
		538978 RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43		U1SBP_HUMAN (1-246): 2.27e-42: 146: 100.00
+	Hs
		441858 RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43		RU17_HUMAN (36-135): 1.04e-38: 141: 45.10
+	Hs
		442037 RSMN_HUMAN (1-212): 4.46e-39: 137: 100.00		RU17_HUMAN (36-135): 1.04e-38: 141: 45.10
+	Mm
		646096 RSMB_MOUSE (1-168): 3.04e-45: 152: 96.43		TIA1_MOUSE (19-227): 8.45e-21: 91.7: 10.05
+	Hs
		538845 RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43		CSTF2_HUMAN (34-125): 1.25e-15: 77.5: 31.52
+	Sp
		143353 RSMB_SCHPO (6-156): 1.85e-18: 80.8: 44.74		RU17_SCHPO (23-139): 8.84e-40: 139: 42.02
+	Sc
		766941 RSMB_YEAST (1-165): 2.64e-36: 128: 28.72		RU17_YEAST (36-197): 5.03e-18: 82.9: 30.18
+	Hs
		963541 LFG1_HUMAN (117-223): 7.43e-09: 57.3: 19.63		TIAR_HUMAN (19-196): 3.29e-19: 87.1: 11.73