HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	10844022
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0044877 - protein-containing complex binding GO:0097110 - scaffold protein binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 724
+	Mm
		928550 DYL1_MOUSE (1-89): 1.96e-46: 145: 100.00		DLG4_MOUSE (1-724): 0: 667: 99.59
+	Hs
		942366 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		DLG4_HUMAN (1-724): 0: 667: 100.00
+	Hs
		928313 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		DLG2_HUMAN (225-474): 2.32e-18: 92.1: 21.09
+	Hs
		1077286 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		DLG2_HUMAN (225-474): 2.32e-18: 92.1: 21.09
+	Hs
		928408 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		DLG5_HUMAN (40-245): 4.76e-17: 88.2: 32.54
+	Hs
		1255119 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		DLG5_HUMAN (40-245): 4.76e-17: 88.2: 32.54
+	Rn
		928570 DYL1_RAT (1-89): 1.96e-46: 145: 100.00		DLG3_RAT (221-548): 5.99e-15: 80.9: 18.55