HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: KANK1 (Q14678)
KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein)
Gene: KANK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 1352
+	Hs
		1057147 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		KANK1_HUMAN (1-1352): 0: 939: 99.26
+	Hs
		928335 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		KANK2_HUMAN (796-1328): 1.67e-76: 274: 34.21
+	Hs
		1144747 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		KANK2_HUMAN (796-1328): 1.67e-76: 274: 34.21
+	Hs
		928334 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		Q5W0W2_HUMAN (978-1352): 1.29e-79: 269: 97.34
+	Hs
		928341 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		KANK3_HUMAN (818-1350): 4.35e-71: 257: 34.02
+	Hs
		928374 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		MIB1_HUMAN (836-1274): 1.9e-32: 139: 13.90