HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: LCA5 (Q86VQ0)
Lebercilin (Leber congenital amaurosis 5 protein)
Gene: LCA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	26638075, 35271311, unassigned1272
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005929 - cilium GO:0044877 - protein-containing complex binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 697
+	Hs
		1202246 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		LCA5_HUMAN (1-697): 1.31e-79: 269: 100.00
+	Hs
		1189784 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MYH14_HUMAN (48-530): 2.28e-23: 108: 14.09
+	Hs
		551662 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21
+	Hs
		928339 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		MRCKG_HUMAN (80-478): 2.56e-10: 66.1: 13.40
+	Hs
		928410 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		RBCC1_HUMAN (123-533): 3.58e-10: 65.8: 16.55
+	Hs
		148656 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		CTRO_HUMAN (46-497): 3.91e-10: 65.4: 12.14
+	Hs
		1150626 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MRCKG_HUMAN (80-478): 2.56e-10: 66.1: 13.40