Protein: NOTC1
Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]

Gene: NOTC1, Notch1
Organism: Mus musculus
Interactions: 23
UniProt ID: Q01705

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001554 - luteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

724965

SUH
Recombining binding protein suppressor of hairless

6

9

Small-scale

0.942

High

1032088

ITCH
E3 ubiquitin-protein ligase Itchy

2

15

Small-scale

0.834

High

1032083

DLL1
Delta-like protein 1

1

17

Small-scale

0.647

High

405588

GRAB
Granzyme B(G,H)

1

12

Small-scale

0.618

High

1032086

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

12

Small-scale

0.618

High

1032094

EGFL7
Epidermal growth factor-like protein 7

1

19

Small-scale

0.618

High

1032085

MAML1
Mastermind-like protein 1

1

13

Small-scale

0.575

High

1032084

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

0

Small-scale

0.513

High

1032092

WDR12
Ribosome biogenesis protein WDR12

1

17

Small-scale

0.501

High

1032080

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

6

Small-scale

0.500

High

1032090

KAT2B
Histone acetyltransferase KAT2B

1

7

Small-scale

0.481

High

1032091

KAT2A
Histone acetyltransferase KAT2A

1

10

Small-scale

0.481

High

236488

EOMES
Eomesodermin homolog

1

2

Small-scale

0.479

High

449239

TNFA
Tumor necrosis factor

1

1

Small-scale

0.479

High

890089

PSN1
Presenilin-1

1

11

Small-scale

0.479

High

1032081

XIAP
E3 ubiquitin-protein ligase XIAP

1

15

Small-scale

0.479

High

1032082

PSN2
Presenilin-2

1

11

Small-scale

0.479

High

1032087

SENP7
Sentrin-specific protease 7

1

3

Small-scale

0.479

High

1032093

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

Small-scale

0.479

High

1032095

NUMB
Protein numb homolog

1

8

Small-scale

0.479

High

533148

PERF
Perforin-1

1

0

Small-scale

0.458

High

713198

NOS2
Nitric oxide synthase, inducible

1

0

Small-scale

0.458

High

1032089

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

2

Small-scale

0.457

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025