HitPredict

Interactor 1: PDI (P54399)
Protein disulfide-isomerase (PDI) (dPDI) (EC 5.3.4.1)
Gene: PDI

Interactor 2: Q9VAY2 (Q9VAY2)
Heat shock protein 83 (HSP 82)
Gene: Gp93

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005783 - endoplasmic reticulum GO:0006457 - protein folding GO:0012505 - endomembrane system GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 496 Dm			1 787
+	Dm
		1191685 Q3YMU0_DROME (3-490): 4.36e-107: 329: 32.13		Q9VAY2_DROME (1-787): 0: 967: 100.00
+	Hs
		573566 DJC10_HUMAN (77-475): 3.75e-54: 196: 15.63		ENPL_HUMAN (1-752): 0: 994: 61.38
+	Hs
		566531 PDIA4_HUMAN (237-496): 2.28e-38: 150: 21.21		ENPL_HUMAN (1-752): 0: 994: 61.38
+	Sc
		578797 PDI_YEAST (15-481): 1.41e-89: 285: 28.92		HSC82_YEAST (72-783): 0: 840: 46.19
+	Hs
		573347 PDIA3_HUMAN (367-494): 2.85e-30: 125: 32.31		ENPL_HUMAN (1-752): 0: 994: 61.38
+	Rn
		801672 PDIA4_RAT (367-494): 3.25e-24: 108: 33.59		ENPL_RAT (1-774): 0: 1001: 60.54
+	Hs
		573483 PDIA6_HUMAN (372-461): 5.64e-09: 60.1: 35.56		ENPL_HUMAN (1-752): 0: 994: 61.38
+	Dm
		1465255 PDIA6_DROME (372-461): 5.99e-10: 63.2: 36.67		Q9VAY2_DROME (1-787): 0: 967: 100.00