Interactor 1: SYYC (P54577)
Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed]
Gene: YARS1
Interactor 2: SYYC (P54577)
Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed]
Gene: YARS1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25533949 |
| Identification Methods | x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | tRNA-synt_1b~tRNA-synt_1b, tRNA_bind~tRNA_bind |
| Common GO terms | GO:0000049 - tRNA binding GO:0003723 - RNA binding GO:0004831 - tyrosine-tRNA ligase activity GO:0005153 - interleukin-8 receptor binding GO:0005524 - ATP binding and 9 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025