HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005737 - cytoplasm GO:0031941 - filamentous actin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 1117
+	Hs
		724859 ACTBL_HUMAN (2-375): 0: 734: 91.44		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		725637 ACTB_HUMAN (1-375): 0: 604: 98.93		ACTN2_HUMAN (1009-1115): 3.7e-48: 188: 41.67
+	Hs
		211548 ACTB_HUMAN (1-375): 0: 604: 98.93		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Dm
		361167 ACT4_DROME (2-375): 0: 592: 94.65		ACTN_DROME (1009-1116): 2.32e-50: 195: 37.62
+	Hs
		211560 ACTC_HUMAN (2-375): 0: 595: 94.39		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Sp
		142705 ACT_SCHPO (1-375): 0: 594: 91.47		AIN1_SCHPO (1008-1117): 3.98e-49: 187: 36.61
+	Hs
		211561 ACTS_HUMAN (2-375): 0: 594: 93.85		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Mm
		892205 ACTB_MOUSE (1-375): 0: 604: 98.93		MYH9_MOUSE (1-938): 2.15e-39: 162: 8.52
+	Oc
		933099 ACTS_RABIT (2-375): 0: 594: 93.85		Q07931_RABIT (890-1115): 3.12e-47: 172: 22.91
+	Hs
		724738 ACTB_HUMAN (1-375): 0: 604: 98.93		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		724762 ACTG_HUMAN (1-375): 0: 604: 100.00		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Rn
		892236 ACTB_RAT (1-375): 0: 604: 98.93		MYH10_RAT (213-1079): 4.97e-34: 144: 10.80
+	Hs
		724766 ACTC_HUMAN (2-375): 0: 595: 94.39		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		724767 ACTS_HUMAN (2-375): 0: 594: 93.85		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		725136 ACTC_HUMAN (2-375): 0: 595: 94.39		MYH10_HUMAN (213-1075): 1.21e-33: 143: 10.62
+	Hs
		725135 ACTH_HUMAN (2-375): 0: 592: 94.39		MYH10_HUMAN (213-1075): 1.21e-33: 143: 10.62
+	Dm
		404232 ACT6_DROME (2-375): 0: 596: 95.46		MYSA_DROME (9-775): 1.21e-27: 123: 9.63
+	Rn
		892228 ACTB_RAT (1-375): 0: 604: 98.93		MYH9_RAT (2-602): 3.58e-25: 115: 10.32
+	Dm
		361160 ACT4_DROME (2-375): 0: 592: 94.65		MYSA_DROME (9-775): 1.21e-27: 123: 9.63
+	Hs
		506816 ACTB_HUMAN (1-375): 0: 604: 98.93		SPTB1_HUMAN (1012-1115): 7.3e-16: 85.5: 47.62