HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1121
+	Hs
		1153256 POTEE_HUMAN (1-375): 0: 729: 91.47		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		932211 ACTC_HUMAN (2-375): 0: 595: 94.39		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		787164 POTEE_HUMAN (1-375): 0: 729: 91.47		RHG25_HUMAN (141-809): 5.84e-56: 208: 14.89
+	Hs
		1164377 POTEE_HUMAN (1-375): 0: 729: 91.47		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		1122505 ACTBL_HUMAN (2-375): 0: 734: 91.44		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		891894 ACTB_HUMAN (1-375): 0: 604: 98.93		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		929924 ACTG_HUMAN (1-375): 0: 604: 100.00		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		892047 ACTB_HUMAN (1-375): 0: 604: 98.93		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Ce
		86418 ACT2_CAEEL (2-375): 0: 602: 97.06		C1P635_CAEEL (7-464): 1.64e-44: 177: 11.64
+	Hs
		915510 ACTA_HUMAN (2-375): 0: 594: 94.39		SMUF2_HUMAN (3-213): 6.3e-48: 185: 18.18
+	Hs
		933057 ACTS_HUMAN (2-375): 0: 594: 93.85		SMUF2_HUMAN (3-213): 6.3e-48: 185: 18.18
+	Hs
		125356 ACTG_HUMAN (1-375): 0: 604: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		930006 ACTG_HUMAN (1-375): 0: 604: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		932378 ACTC_HUMAN (2-375): 0: 595: 94.39		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		932156 ACTC_HUMAN (2-375): 0: 595: 94.39		MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84
+	Sc
		765355 ACT_YEAST (1-375): 0: 592: 89.07		RSP5_YEAST (29-320): 3.05e-17: 89.3: 13.99