HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 693
+	Hs
		554315 ACTBL_HUMAN (2-375): 0: 734: 91.44		MUC1_HUMAN (23-434): 8.02e-18: 90.2: 8.89
+	Hs
		846794 ACTBL_HUMAN (2-375): 0: 734: 91.44		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		1122431 ACTBL_HUMAN (2-375): 0: 734: 91.44		SRCAP_HUMAN (28-590): 2.21e-09: 63.2: 8.69
+	Mm
		929785 ACTG_MOUSE (1-375): 0: 604: 100.00		SMCA4_MOUSE (201-665): 3.01e-44: 173: 11.52
+	Dm
		501486 ACT1_DROME (2-375): 0: 600: 98.13		BRM_DROME (165-665): 1e-43: 172: 12.74
+	Dm
		361138 ACT2_DROME (2-375): 0: 598: 97.59		BRM_DROME (165-665): 1e-43: 172: 12.74
+	Mm
		929795 ACTG_MOUSE (1-375): 0: 604: 100.00		SMCA2_MOUSE (121-665): 2.44e-36: 149: 11.87
+	Xl
		292752 ACTB_XENLA (1-375): 0: 604: 98.93		Q4VQ79_XENLA (219-665): 4.37e-32: 136: 12.03
+	Hs
		554290 ACTA_HUMAN (2-375): 0: 594: 94.39		MUC1_HUMAN (23-434): 8.02e-18: 90.2: 8.89
+	Mm
		929800 ACTG_MOUSE (1-375): 0: 604: 100.00		EP400_MOUSE (136-450): 6.08e-14: 78.2: 16.15
+	Hs
		891853 ACTB_HUMAN (1-375): 0: 604: 98.93		SRCAP_HUMAN (28-590): 2.21e-09: 63.2: 8.69
+	Hs
		929905 ACTG_HUMAN (1-375): 0: 604: 100.00		SRCAP_HUMAN (28-590): 2.21e-09: 63.2: 8.69
+	Hs
		846910 ACTB_HUMAN (1-375): 0: 604: 98.93		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		846917 ACTG_HUMAN (1-375): 0: 604: 100.00		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		846742 ACTC_HUMAN (2-375): 0: 595: 94.39		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		932219 ACTC_HUMAN (2-375): 0: 595: 94.39		SRCAP_HUMAN (28-590): 2.21e-09: 63.2: 8.69
+	Hs
		203220 ACTC_HUMAN (2-375): 0: 595: 94.39		SYNJ1_HUMAN (303-658): 3.22e-09: 62.5: 9.55
+	Hs
		846918 ACTC_HUMAN (2-375): 0: 595: 94.39		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		846919 ACTS_HUMAN (2-375): 0: 594: 93.85		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81