HitPredict

Interactor 1: ACTH (P63267)
Actin, gamma-enteric smooth muscle (EC 3.6.4.-) (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin) [Cleaved into: Actin, gamma-enteric smooth muscle, intermediate form]
Gene: ACTG2

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36574265
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Hs			1 636
+	Hs
		891775 ACTB_HUMAN (1-376): 0: 601: 93.35		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		929867 ACTG_HUMAN (3-376): 0: 601: 94.39		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		932981 ACTS_HUMAN (2-376): 0: 598: 98.13		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		724859 ACTBL_HUMAN (1-376): 0: 713: 87.77		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		892118 ACTB_HUMAN (1-376): 0: 601: 93.35		SMC3_HUMAN (278-527): 2.28e-43: 169: 25.09
+	Mm
		892198 ACTB_MOUSE (1-376): 0: 601: 93.35		FTM_MOUSE (17-526): 3.12e-25: 113: 15.30
+	Mm
		892205 ACTB_MOUSE (1-376): 0: 601: 93.35		MYH9_MOUSE (1-554): 1.7e-19: 95.7: 10.65
+	Rn
		892236 ACTB_RAT (1-376): 0: 601: 93.35		MYH10_RAT (2-506): 1.83e-19: 95.4: 11.16
+	Hs
		148662 ACTC_HUMAN (2-376): 0: 598: 98.67		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Dm
		116373 ACT1_DROME (1-376): 0: 603: 94.15		M9PI41_DROME (133-532): 3.07e-14: 78.8: 19.04
+	Dm
		116372 ACT2_DROME (1-376): 0: 601: 93.88		M9PI41_DROME (133-532): 3.07e-14: 78.8: 19.04
+	Hs
		725135 ACTH_HUMAN (1-376): 0: 598: 100.00		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		725136 ACTC_HUMAN (2-376): 0: 598: 98.67		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		892003 ACTB_HUMAN (1-376): 0: 601: 93.35		CP250_HUMAN (63-566): 3.97e-11: 68.8: 11.57
+	Rn
		92841 ACTB_RAT (1-376): 0: 601: 93.35		CTRO_RAT (224-544): 1.01e-09: 64.3: 11.49
+	Hs
		724738 ACTB_HUMAN (1-376): 0: 601: 93.35		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		724762 ACTG_HUMAN (3-376): 0: 601: 94.39		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Rn
		892228 ACTB_RAT (1-376): 0: 601: 93.35		MYH9_RAT (260-565): 1.09e-09: 63.8: 13.59
+	Hs
		724766 ACTC_HUMAN (2-376): 0: 598: 98.67		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		724767 ACTS_HUMAN (2-376): 0: 598: 98.13		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33