Protein: TFB1M
Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (h-mtTFB) (h-mtTFB1) (hTFB1M) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)

Gene: TFB1M
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q8WVM0

Gene Ontology (top 5):
GO:0000154 - rRNA modification
GO:0000179 - rRNA (adenine-N6,N6-)-dimethyltransferase activity
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

134343

RPOM
DNA-directed RNA polymerase, mitochondrial

1

3

Small-scale

0.724

High

532811

CH60
60 kDa heat shock protein, mitochondrial

2

3

High-throughput

0.628

High

1215332

DCAF8
DDB1- and CUL4-associated factor 8

2

1

High-throughput

0.628

High

904968

MECP2
Methyl-CpG-binding protein 2

2

0

High-throughput

0.602

High

914684

RM12
Large ribosomal subunit protein bL12m

2

0

High-throughput

0.602

High

946512

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.602

High

1024114

TFAM
Transcription factor A, mitochondrial

1

1

Small-scale

0.578

High

810247

RL3
Large ribosomal subunit protein uL3

2

1

High-throughput

0.571

High

191726

MAGB2
Melanoma-associated antigen B2

2

2

High-throughput

0.549

High

521835

H14
Histone H1.4

1

2

High-throughput

0.536

High

693866

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.536

High

969334

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.536

High

969999

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

978630

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.536

High

1213294

RM02
Large ribosomal subunit protein uL2m

1

1

High-throughput

0.536

High

1358281

ZRAN1
Ubiquitin thioesterase ZRANB1

2

2

High-throughput

0.533

High

396593

ESR1
Estrogen receptor

2

2

High-throughput

0.521

High

869203

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

1011326

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.513

High

1049609

1433F
14-3-3 protein eta

1

0

High-throughput

0.513

High

1099457

SRSF6
Serine/arginine-rich splicing factor 6

1

0

High-throughput

0.513

High

1358270

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1358284

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

1358287

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.513

High

1358288

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.513

High

1358289

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

125847

AP4M1
AP-4 complex subunit mu-1

1

1

High-throughput

0.489

High

338920

CBX6
Chromobox protein homolog 6

1

1

High-throughput

0.489

High

1291091

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.489

High

372685

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

472922

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

766720

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

937833

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

1067540

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

1207412

HABP4
Intracellular hyaluronan-binding protein 4

1

3

High-throughput

0.479

High

1334692

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.479

High

1358280

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

1358285

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.479

High

242410

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

401207

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

1346862

SNIP1
Smad nuclear-interacting protein 1

1

0

Small-scale

0.458

High

430165

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

1112110

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.445

High

157663

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.437

High

315812

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.437

High

319933

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.437

High

581198

RAC2
Ras-related C3 botulinum toxin substrate 2

1

2

High-throughput

0.437

High

607621

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

2

High-throughput

0.437

High

955419

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.437

High

962320

RHOA
Transforming protein RhoA

1

2

High-throughput

0.437

High

1087675

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

1

High-throughput

0.437

High

1126138

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.437

High

1135005

CUL7
Cullin-7

1

1

High-throughput

0.437

High

1137889

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.437

High

1151799

RHOH
Rho-related GTP-binding protein RhoH

1

3

High-throughput

0.437

High

1178281

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

1254814

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1276542

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1327099

FBXL6
F-box/LRR-repeat protein 6

1

1

High-throughput

0.437

High

1358269

DPF3
Zinc finger protein DPF3

1

1

Small-scale

0.437

High

1358271

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

1358275

RIOK1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.437

High

1358277

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

1358278

RHOJ
Rho-related GTP-binding protein RhoJ

1

3

High-throughput

0.437

High

1358282

XPO7
Exportin-7

1

3

High-throughput

0.437

High

686307

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.426

High

1009265

PRR3
Proline-rich protein 3

1

0

High-throughput

0.426

High

1123360

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.426

High

1132398

CASP8
Caspase-8

1

0

High-throughput

0.426

High

1239895

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.426

High

1358274

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.426

High

1358283

ZN346
Zinc finger protein 346

1

0

High-throughput

0.426

High

944007

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

1037293

H11
Histone H1.1

1

2

High-throughput

0.407

High

177396

ARHGB
Rho guanine nucleotide exchange factor 11

2

0

High-throughput

0.298

High

1102351

GRB10
Growth factor receptor-bound protein 10

2

0

High-throughput

0.298

High

657277

KALM
Anosmin-1

1

0

High-throughput

0.279

Low

1036673

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

0

High-throughput

0.279

Low

1127445

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1281431

ZN467
Zinc finger protein 467

1

0

High-throughput

0.279

Low

1358272

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

1358286

BAIP2
BAR/IMD domain-containing adapter protein 2

1

0

High-throughput

0.279

Low

132183

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.249

Low

272344

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

279434

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

710397

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.249

Low

942777

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

652659

GNLY
Granulysin

1

0

High-throughput

0.232

Low

1315234

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.232

Low

1358273

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.232

Low

1358276

ZSA5A
Zinc finger and SCAN domain-containing protein 5A

1

0

High-throughput

0.232

Low

1358279

H2AW
Core histone macro-H2A.2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025