Interactor 1: VATE (P54611)
V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 26 kDa subunit) (Vacuolar proton pump subunit E)
Gene: Vha26

Interactor 2: VATA2 (Q27331)
V-type proton ATPase catalytic subunit A isoform 2 (V-ATPase subunit A 2) (EC 7.1.2.2) (V-ATPase 69 kDa subunit 2) (Vacuolar proton pump subunit alpha 2)
Gene: Vha68-2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-synt_ab~vATP-synt_E, ATP-synt_ab_N~vATP-synt_E
Common GO terms GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005886 - plasma membrane
GO:0033181 - plasma membrane proton-transporting V-type ATPase complex
GO:0046961 - proton-transporting ATPase activity, rotational mechanism
GO:1902600 - proton transmembrane transport
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 226
Dm

1 614
+ Dm
+ Hs
+ Mm
+ Dm
+ Sc
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025