HitPredict

Interactor 1: ACTC (P68033)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: Actc1

Interactor 2: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30562941
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007015 - actin filament organization GO:0030027 - lamellipodium GO:0030175 - filopodium
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 377 Mm			1 817
+	Rn
		192517 ACTB_RAT (4-377): 0: 599: 94.12		NEB2_RAT (1-817): 2.42e-118: 379: 98.90
+	Rn
		192522 ACTS_RAT (1-377): 0: 599: 98.94		NEB2_RAT (1-817): 2.42e-118: 379: 98.90
+	Mm
		892184 ACTB_MOUSE (4-377): 0: 599: 94.12		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Mm
		933086 ACTS_MOUSE (1-377): 0: 599: 98.94		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Hs
		891987 ACTB_HUMAN (4-377): 0: 599: 94.12		NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84
+	Hs
		929975 ACTG_HUMAN (4-377): 0: 599: 94.39		NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84
+	Hs
		933041 ACTS_HUMAN (1-377): 0: 599: 98.94		NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84
+	Hs
		915484 ACTA_HUMAN (1-377): 0: 596: 98.41		NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84
+	Hs
		892106 ACTB_HUMAN (4-377): 0: 599: 94.12		NEB1_HUMAN (1-817): 1.2e-100: 338: 46.50
+	Hs
		930050 ACTG_HUMAN (4-377): 0: 599: 94.39		NEB1_HUMAN (1-817): 1.2e-100: 338: 46.50
+	Mm
		929790 ACTG_MOUSE (4-377): 0: 599: 94.39		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Mm
		892179 ACTB_MOUSE (4-377): 0: 599: 94.12		INADL_MOUSE (475-595): 1.73e-11: 70.4: 21.95
+	Hs
		929935 ACTG_HUMAN (4-377): 0: 599: 94.39		DLG5_HUMAN (424-594): 7.08e-09: 62: 18.75