Protein: KCC1A
Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)

Gene: KCC1A, CAMK1
Organism: Homo sapiens
Interactions: 90
UniProt ID: Q14012

Gene Ontology (top 5):
GO:0004683 - calcium/calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1120028

KCC1D
Calcium/calmodulin-dependent protein kinase type 1D

4

17

High-throughput

0.903

High

640166

EPHA1
Ephrin type-A receptor 1

2

6

High-throughput

0.811

High

902836

BLK
Tyrosine-protein kinase Blk

2

7

High-throughput

0.776

High

1120025

MARK2
Serine/threonine-protein kinase MARK2

1

8

Small-scale

0.756

High

857329

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

1

Small-scale

0.724

High

943575

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

12

High-throughput

0.698

High

1119728

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

4

15

High-throughput

0.692

High

322103

CDK14
Cyclin-dependent kinase 14

1

6

High-throughput

0.691

High

471830

RU2B
U2 small nuclear ribonucleoprotein B''

1

2

High-throughput

0.691

High

521345

ARAF
Serine/threonine-protein kinase A-Raf

1

8

High-throughput

0.691

High

638413

FPR1
fMet-Leu-Phe receptor

1

1

High-throughput

0.691

High

692694

CALL3
Calmodulin-like protein 3

1

20

High-throughput

0.691

High

837223

ACTY
Beta-centractin

1

5

High-throughput

0.691

High

1029469

SRSF2
Serine/arginine-rich splicing factor 2

1

2

High-throughput

0.691

High

1120017

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

3

High-throughput

0.691

High

1120030

KKCC1
Calcium/calmodulin-dependent protein kinase kinase 1

1

17

High-throughput

0.691

High

1120036

KCC1G
Calcium/calmodulin-dependent protein kinase type 1G

1

17

High-throughput

0.691

High

927291

ATX1
Ataxin-1

3

1

High-throughput

0.660

High

549151

CDK4
Cyclin-dependent kinase 4

1

5

Small-scale

0.647

High

1120037

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

18

Small-scale

0.647

High

1120038

CC106
Coiled-coil domain-containing protein 106

3

0

High-throughput

0.638

High

133252

P2Y10
Putative P2Y purinoceptor 10

1

1

High-throughput

0.618

High

1101482

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.618

High

1120023

BTNL9
Butyrophilin-like protein 9

1

4

High-throughput

0.618

High

318768

RHBT1
Rho-related BTB domain-containing protein 1

1

5

High-throughput

0.618

High

830710

CCNF
Cyclin-F

1

1

High-throughput

0.618

High

1120024

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.618

High

664736

CCND1
G1/S-specific cyclin-D1

1

0

Small-scale

0.614

High

346762

CER1
Cerberus

2

2

High-throughput

0.611

High

1120031

SIA7C
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

3

1

High-throughput

0.609

High

1120018

CDO1
Cysteine dioxygenase type 1

2

0

High-throughput

0.602

High

1120020

PHF19
PHD finger protein 19

2

0

High-throughput

0.602

High

1120029

PNKD
Probable thioesterase PNKD

2

0

High-throughput

0.585

High

702774

5HT2C
5-hydroxytryptamine receptor 2C

1

0

High-throughput

0.578

High

1120033

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

9

High-throughput

0.576

High

231571

PRKY
Putative serine/threonine-protein kinase PRKY

1

7

High-throughput

0.575

High

516338

CALM1
Calmodulin-1

1

20

High-throughput

0.575

High

1120027

CMTD1
Catechol O-methyltransferase domain-containing protein 1

2

1

High-throughput

0.549

High

415557

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.541

High

65751

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

1

High-throughput

0.536

High

128223

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

1

High-throughput

0.536

High

138104

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

High-throughput

0.536

High

166656

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

1

High-throughput

0.536

High

175040

SC16A
Protein transport protein Sec16A

1

4

High-throughput

0.536

High

257847

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

1

High-throughput

0.536

High

300148

GLRX3
Glutaredoxin-3

1

4

High-throughput

0.536

High

330948

KI20A
Kinesin-like protein KIF20A

1

5

High-throughput

0.536

High

388190

GLPA
Glycophorin-A

1

1

High-throughput

0.536

High

700630

PSA5
Proteasome subunit alpha type-5

1

2

High-throughput

0.536

High

932466

KAD2
Adenylate kinase 2, mitochondrial

1

2

High-throughput

0.536

High

1036649

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

15

High-throughput

0.536

High

1042743

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

1

High-throughput

0.536

High

1106189

MYO9B
Unconventional myosin-IXb

1

5

High-throughput

0.536

High

1120034

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

1120035

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.536

High

1120022

CGB2
Choriogonadotropin subunit beta variant 2

2

0

High-throughput

0.528

High

843553

HD
Huntingtin

1

5

High-throughput

0.515

High

1120021

ANR22
Ankyrin repeat domain-containing protein 22

1

4

High-throughput

0.514

High

639343

SCF
Kit ligand

1

0

High-throughput

0.513

High

1120014

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.513

High

1120015

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

0

High-throughput

0.513

High

1120019

SAMTR
S-adenosylmethionine sensor upstream of mTORC1

1

0

High-throughput

0.513

High

1120032

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.513

High

1120039

NEUL
Neurolysin, mitochondrial

1

0

High-throughput

0.513

High

422090

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

994216

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

8

Small-scale

0.501

High

698645

CALX
Calnexin

1

1

High-throughput

0.489

High

867962

GLR
Glucagon receptor

1

1

High-throughput

0.489

High

1116858

MOGS
Mannosyl-oligosaccharide glucosidase

1

1

High-throughput

0.489

High

1120016

UBE3C
Ubiquitin-protein ligase E3C

1

6

High-throughput

0.489

High

1120042

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

1

High-throughput

0.489

High

1120043

MAP10
Microtubule-associated protein 10

1

3

High-throughput

0.489

High

1120041

GCM1
Chorion-specific transcription factor GCMa

1

0

Small-scale

0.480

High

1120047

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

711124

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

4

Small-scale

0.479

High

837611

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

940960

HDAC4
Histone deacetylase 4

1

11

Small-scale

0.479

High

970477

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

1113068

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1120044

HDAC9
Histone deacetylase 9

1

11

Small-scale

0.479

High

1120046

HDAC5
Histone deacetylase 5

1

11

Small-scale

0.479

High

402594

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.458

High

114565

H0YKB7
Interleukin 16

1

14

High-throughput

0.445

High

837395

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

1

High-throughput

0.445

High

1120040

BOLA2
BolA-like protein 2

1

0

High-throughput

0.426

High

1120026

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

71206

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

1120045

PA2GD
Group IID secretory phospholipase A2

1

0

High-throughput

0.279

Low

1120048

PPME1
Protein phosphatase methylesterase 1

1

0

Small-scale

0.261

Low

505285

F153B
Protein FAM153B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025