HitPredict

Interactor 1: ACTS (P68134)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: Acta1

Interactor 2: PRKN (Q9WVS6)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19909785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0010628 - positive regulation of gene expression GO:0032991 - protein-containing complex
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 377 Mm			1 464
+	Mm
		892218 ACTB_MOUSE (5-377): 0: 604: 93.83		PRKN_MOUSE (1-464): 1.15e-144: 423: 100.00
+	Hs
		227131 ACTS_HUMAN (1-377): 0: 605: 100.00		PRKN_HUMAN (1-464): 7.14e-141: 413: 83.66
+	Hs
		227018 ACTB_HUMAN (5-377): 0: 604: 93.83		PRKN_HUMAN (1-464): 7.14e-141: 413: 83.66
+	Hs
		227123 ACTG_HUMAN (4-377): 0: 604: 93.85		PRKN_HUMAN (1-464): 7.14e-141: 413: 83.66
+	Hs
		227128 ACTC_HUMAN (1-377): 0: 604: 98.94		PRKN_HUMAN (1-464): 7.14e-141: 413: 83.66
+	Hs
		227086 ACTA_HUMAN (1-377): 0: 602: 97.88		PRKN_HUMAN (1-464): 7.14e-141: 413: 83.66
+	Hs
		932245 ACTC_HUMAN (1-377): 0: 604: 98.94		CUL9_HUMAN (110-462): 2.02e-66: 233: 18.94
+	Rn
		892231 ACTB_RAT (5-377): 0: 604: 93.83		UBC_RAT (1-180): 1.7e-60: 213: 20.44
+	Hs
		475605 ACTS_HUMAN (1-377): 0: 605: 100.00		UBC_HUMAN (1-77): 1.28e-33: 136: 31.17
+	Hs
		475544 ACTB_HUMAN (5-377): 0: 604: 93.83		UBC_HUMAN (1-77): 1.28e-33: 136: 31.17
+	Hs
		475603 ACTC_HUMAN (1-377): 0: 604: 98.94		UBC_HUMAN (1-77): 1.28e-33: 136: 31.17
+	Zm
		24703 B4F989_MAIZE (1-377): 0: 597: 87.27		A0A1D6IJX7_MAIZE (237-458): 1.09e-25: 113: 22.32