HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: KLF1 (Q13351)
Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF)
Gene: KLF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	9722526
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~zf-C2H2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 362
+	Hs
		586724 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		KLF1_HUMAN (1-362): 1.09e-118: 349: 100.00
+	Hs
		934343 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		ZN480_HUMAN (71-335): 6.97e-95: 294: 18.59
+	Hs
		934431 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		ZN577_HUMAN (224-361): 3.13e-51: 179: 28.17
+	Hs
		586948 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		ZN577_HUMAN (224-361): 3.13e-51: 179: 28.17
+	Mm
		250996 CSK21_MOUSE (1-391): 4.08e-134: 390: 98.72		SP3_MOUSE (258-361): 5.67e-27: 114: 51.89
+	Mm
		292661 CSK21_MOUSE (1-391): 4.08e-134: 390: 98.72		SP1_MOUSE (267-361): 1.26e-26: 113: 55.79
+	Hs
		836124 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		KLF2_HUMAN (262-362): 1.97e-44: 158: 82.18
+	Hs
		835739 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		KLF5_HUMAN (263-361): 1.07e-38: 145: 73.00
+	Hs
		625403 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		KLF10_HUMAN (159-362): 7.18e-30: 121: 41.59
+	Hs
		434952 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		SP1_HUMAN (267-361): 9.06e-27: 113: 56.84
+	Mm
		222413 CSK22_MOUSE (1-334): 4.23e-119: 351: 85.08		SP3_MOUSE (258-361): 5.67e-27: 114: 51.89
+	Mm
		222414 CSK22_MOUSE (1-334): 4.23e-119: 351: 85.08		SP1_MOUSE (267-361): 1.26e-26: 113: 55.79
+	Hs
		435012 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		SP1_HUMAN (267-361): 9.06e-27: 113: 56.84