Protein: PDLI5
PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)

Gene: PDLI5, PDLIM5
Organism: Homo sapiens
Interactions: 139
UniProt ID: Q96HC4

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0003779 - actin binding
GO:0005080 - protein kinase C binding
GO:0005829 - cytosol
GO:0005912 - adherens junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1080752

ZYX
Zyxin

2

20

High-throughput

0.815

High

1293402

PDLI7
PDZ and LIM domain protein 7

2

19

High-throughput

0.811

High

970595

ID2
DNA-binding protein inhibitor ID-2

1

2

Small-scale

0.756

High

234566

DSCAM
Cell adhesion molecule DSCAM

1

5

High-throughput

0.698

High

363260

FINC
Fibronectin

1

4

High-throughput

0.691

High

1033526

ILK
Integrin-linked protein kinase

1

18

High-throughput

0.691

High

971135

ID3
DNA-binding protein inhibitor ID-3

1

2

Small-scale

0.647

High

228350

PRKN
E3 ubiquitin-protein ligase parkin

3

12

High-throughput

0.640

High

808847

YAP1
Transcriptional coactivator YAP1

3

20

Small-scale

0.640

High

1134181

PHF19
PHD finger protein 19

2

1

High-throughput

0.628

High

175706

TRI18
E3 ubiquitin-protein ligase Midline-1

1

18

Small-scale

0.618

High

914280

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.618

High

1206026

MIB1
E3 ubiquitin-protein ligase MIB1

1

9

Small-scale

0.618

High

1293407

ZO2
Tight junction protein ZO-2

1

9

High-throughput

0.618

High

1293409

TES
Testin

1

19

High-throughput

0.618

High

1293393

SYT11
Synaptotagmin-11

2

1

High-throughput

0.611

High

750413

COIL
Coilin

2

0

High-throughput

0.601

High

987837

GABP1
GA-binding protein subunit beta-1

1

6

High-throughput

0.594

High

1044045

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

13

High-throughput

0.584

High

780980

ID1
DNA-binding protein inhibitor ID-1

1

2

Small-scale

0.579

High

906077

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

6

High-throughput

0.575

High

262543

TULP3
Tubby-related protein 3

2

1

High-throughput

0.574

High

1241445

NF2IP
NFATC2-interacting protein

2

1

High-throughput

0.574

High

1293415

EMIL1
EMILIN-1

2

5

High-throughput

0.574

High

1293386

CC136
Coiled-coil domain-containing protein 136

2

9

High-throughput

0.573

High

889368

KR107
Keratin-associated protein 10-7

1

4

High-throughput

0.573

High

1149285

K1C40
Keratin, type I cytoskeletal 40

1

7

High-throughput

0.573

High

504572

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.571

High

529560

CFTR
Cystic fibrosis transmembrane conductance regulator

2

5

High-throughput

0.571

High

1234547

SH2D3
SH2 domain-containing protein 3C

2

20

High-throughput

0.571

High

385342

NTRK1
High affinity nerve growth factor receptor

1

17

High-throughput

0.553

High

884563

RAB25
Ras-related protein Rab-25

1

1

High-throughput

0.553

High

1171233

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.553

High

408660

KPCB
Protein kinase C beta type

1

16

Small-scale

0.552

High

1293398

TRI39
E3 ubiquitin-protein ligase TRIM39

1

4

High-throughput

0.541

High

66691

ZN785
Zinc finger protein 785

1

1

High-throughput

0.536

High

323965

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.536

High

1170446

UBR3
E3 ubiquitin-protein ligase UBR3

1

1

High-throughput

0.536

High

1251886

RIN3
Ras and Rab interactor 3

1

8

High-throughput

0.536

High

749773

BRCA1
Breast cancer type 1 susceptibility protein

2

7

High-throughput

0.533

High

147551

SOCS6
Suppressor of cytokine signaling 6

1

20

High-throughput

0.515

High

434422

TPM2
Tropomyosin beta chain

1

11

High-throughput

0.515

High

871734

HSP72
Heat shock-related 70 kDa protein 2

1

4

High-throughput

0.515

High

1063555

SUZ12
Polycomb protein SUZ12

1

2

High-throughput

0.515

High

535530

GFAP
Glial fibrillary acidic protein

1

15

High-throughput

0.515

High

791863

HD
Huntingtin

1

3

High-throughput

0.515

High

868678

ATX1
Ataxin-1

1

1

High-throughput

0.515

High

276477

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.513

High

534443

DHB1
17-beta-hydroxysteroid dehydrogenase type 1

1

0

High-throughput

0.513

High

829314

SYHM
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1169283

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.513

High

1218901

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1138070

GFI1B
Zinc finger protein Gfi-1b

1

2

High-throughput

0.508

High

1263763

JPH3
Junctophilin-3

1

0

High-throughput

0.493

High

1293405

GEMI8
Gem-associated protein 8

1

0

High-throughput

0.493

High

571194

EGLN
Endoglin

1

3

High-throughput

0.489

High

648579

CALL3
Calmodulin-like protein 3

1

1

High-throughput

0.489

High

1156925

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

1

3

High-throughput

0.489

High

1285044

ARRD3
Arrestin domain-containing protein 3

1

1

High-throughput

0.489

High

1293411

AT7L1
Ataxin-7-like protein 1

1

3

High-throughput

0.489

High

969104

KPCE
Protein kinase C epsilon type

1

16

Small-scale

0.481

High

1293397

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

2

Small-scale

0.481

High

163141

XPO1
Exportin-1

1

11

High-throughput

0.479

High

295127

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

323000

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

374689

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

13

High-throughput

0.479

High

430301

PROF1
Profilin-1

1

2

Small-scale

0.479

High

443727

VIME
Vimentin

1

15

High-throughput

0.479

High

476201

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

Small-scale

0.479

High

488776

ARAF
Serine/threonine-protein kinase A-Raf

1

11

High-throughput

0.479

High

522130

CADH1
Cadherin-1

1

7

High-throughput

0.479

High

610475

CBL
E3 ubiquitin-protein ligase CBL

1

10

High-throughput

0.479

High

651955

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

717279

CTNB1
Catenin beta-1

1

5

High-throughput

0.479

High

718101

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.479

High

779915

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

880802

HDAC4
Histone deacetylase 4

1

5

High-throughput

0.479

High

891971

ACTB
Actin, cytoplasmic 1

1

12

High-throughput

0.479

High

908962

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

950247

SMAD3
Mothers against decapentaplegic homolog 3

1

7

Small-scale

0.479

High

1024398

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

4

High-throughput

0.479

High

1025195

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

2

High-throughput

0.479

High

1030419

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.479

High

1036813

SQSTM
Sequestosome-1

1

14

High-throughput

0.479

High

1042276

CUL3
Cullin-3

1

13

High-throughput

0.479

High

1052735

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

20

Small-scale

0.479

High

1146151

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.479

High

1175960

HAKAI
E3 ubiquitin-protein ligase Hakai

1

1

Small-scale

0.479

High

1188713

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

1199668

ZN598
E3 ubiquitin-protein ligase ZNF598

1

4

Small-scale

0.479

High

1200571

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

1219215

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

4

High-throughput

0.479

High

1239148

ZBT38
Zinc finger and BTB domain-containing protein 38

1

1

Small-scale

0.479

High

1254223

BICD2
Protein bicaudal D homolog 2

1

17

High-throughput

0.479

High

1254707

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

1

Small-scale

0.479

High

1266530

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1267085

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

1272530

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.479

High

1281815

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

1291682

BICD1
Protein bicaudal D homolog 1

1

17

High-throughput

0.479

High

1293389

RANB9
Ran-binding protein 9

1

3

High-throughput

0.479

High

1293391

NECD
Necdin

1

4

High-throughput

0.479

High

1293392

TRI56
E3 ubiquitin-protein ligase TRIM56

1

17

Small-scale

0.479

High

1293394

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

1293395

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

3

Small-scale

0.479

High

1293400

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

3

Small-scale

0.479

High

1293401

BIRC6
Baculoviral IAP repeat-containing protein 6

1

4

Small-scale

0.479

High

1293406

HDAC6
Histone deacetylase 6

1

5

High-throughput

0.479

High

1293408

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1293410

HERC5
E3 ISG15--protein ligase HERC5

1

9

Small-scale

0.479

High

1293412

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

Small-scale

0.479

High

1293413

FBW1A
F-box/WD repeat-containing protein 1A

1

4

High-throughput

0.479

High

1293414

ADIP
Afadin- and alpha-actinin-binding protein

1

2

High-throughput

0.479

High

1293399

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

134551

FCN1
Ficolin-1

1

2

Small-scale

0.457

High

1155934

Q6NSK7
RIN3 protein

1

13

High-throughput

0.457

High

1293403

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

553436

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.437

High

962699

CAC1B
Voltage-dependent N-type calcium channel subunit alpha-1B

1

1

Small-scale

0.437

High

1162105

RHDF2
Inactive rhomboid protein 2

1

3

High-throughput

0.437

High

1172717

CE128
Centrosomal protein of 128 kDa

1

12

High-throughput

0.437

High

1256019

RHBL4
Rhomboid-related protein 4

1

3

High-throughput

0.437

High

1269355

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

1293388

CIC
Protein capicua homolog

1

7

High-throughput

0.437

High

1293390

RING2
E3 ubiquitin-protein ligase RING2

1

7

High-throughput

0.437

High

1293396

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.437

High

1293404

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

4

High-throughput

0.437

High

1105

SIM26
Small integral membrane protein 26

1

2

High-throughput

0.407

High

353893

IGHG4
Immunoglobulin heavy constant gamma 4

1

3

High-throughput

0.407

High

883257

RWD2B
RWD domain-containing protein 2B

3

0

High-throughput

0.347

High

1253374

METL6
tRNA N(3)-methylcytidine methyltransferase METTL6

3

0

High-throughput

0.347

High

207737

DENR
Density-regulated protein

2

0

High-throughput

0.328

High

473069

BNIP5
Protein BNIP5

1

0

High-throughput

0.279

Low

1288064

RMD1
Regulator of microtubule dynamics protein 1

1

0

High-throughput

0.279

Low

976201

TFF2
Trefoil factor 2

1

0

High-throughput

0.268

Low

80920

B6ZDN3
Doublecortin domain containing 1

1

0

High-throughput

0.249

Low

352216

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1236439

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

Small-scale

0.249

Low

1293387

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024