HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: AUTS2 (Q8WXX7)
Autism susceptibility gene 2 protein
Gene: AUTS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.728

Property	Details
Experiments	25519132, 27705803, 33961781, 32707033, 36736316
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 1259
+	Hs
		1243539 CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47		AUTS2_HUMAN (1-1259): 1.57e-142: 466: 100.00
+	Hs
		586885 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		AUTS2_HUMAN (1-1259): 1.57e-142: 466: 100.00
+	Mm
		1141307 CSK21_MOUSE (1-391): 4.08e-134: 390: 98.72		Q6PED7_MOUSE (637-1259): 1.68e-63: 230: 92.01
+	Mm
		222422 CSK22_MOUSE (1-334): 4.23e-119: 351: 85.08		Q6PED7_MOUSE (637-1259): 1.68e-63: 230: 92.01
+	Hs
		934494 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		554284 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		MUC1_HUMAN (21-960): 4.41e-54: 209: 12.26
+	Hs
		934488 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		1243555 CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		586998 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		92118 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		NACAM_HUMAN (357-1258): 1.96e-23: 110: 8.08
+	Hs
		586991 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		297825 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		K0754_HUMAN (899-1257): 1.15e-13: 78.6: 11.20
+	Hs
		934410 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		934167 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		MDC1_HUMAN (700-1257): 7.36e-10: 65.9: 8.20
+	Hs
		625528 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		TITIN_HUMAN (60-591): 1.15e-09: 65.3: 11.92
+	Sc
		584735 CSK22_YEAST (2-326): 1.7e-120: 354: 59.51		SEC31_YEAST (473-885): 6.28e-09: 62.6: 13.41
+	Sc
		550035 CSK21_YEAST (1-329): 6.88e-113: 336: 54.32		SEC31_YEAST (473-885): 6.28e-09: 62.6: 13.41