HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25281560, 34349018
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 130
+	Hs
		1086182 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A2A_HUMAN (1-130): 4.66e-67: 200: 100.00
+	Hs
		391649 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470336 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Hs
		1086192 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A3_HUMAN (1-130): 6.2e-67: 199: 97.69
+	Hs
		391723 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470399 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Hs
		935170 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A1J_HUMAN (1-128): 2.76e-66: 198: 97.66
+	Hs
		1086293 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A1J_HUMAN (1-128): 2.76e-66: 198: 97.66
+	Hs
		391655 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		470350 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		H2A1_HUMAN (1-130): 6.85e-67: 199: 98.46
+	Hs
		935141 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A1A_HUMAN (1-125): 8.62e-66: 197: 95.20
+	Hs
		1086278 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A1H_HUMAN (1-128): 3.92e-66: 197: 98.44
+	Hs
		934946 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A2B_HUMAN (1-130): 1.54e-65: 196: 94.62
+	Hs
		1086203 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A2B_HUMAN (1-130): 1.54e-65: 196: 94.62
+	Mm
		935458 H31_MOUSE (1-136): 2.8e-62: 188: 100.00		Q8CGP4_MOUSE (1-126): 1.31e-64: 194: 89.68
+	Hs
		934815 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88
+	Hs
		1086165 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88
+	Mm
		952759 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		Q8CGP4_MOUSE (1-126): 1.31e-64: 194: 89.68
+	Hs
		555411 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Hs
		555485 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81