Protein: S22A4
Solute carrier family 22 member 4 (Ergothioneine transporter) (ET transporter) (ETTh) (Organic cation/carnitine transporter 1) (OCTN1)

Gene: S22A4, SLC22A4
Organism: Homo sapiens
Interactions: 190
UniProt ID: Q9H015

Gene Ontology (top 5):
GO:0005277 - acetylcholine transmembrane transporter activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005886 - plasma membrane
GO:0006641 - triglyceride metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

283281

S22A5
Organic cation/carnitine transporter 2

1

5

High-throughput

0.691

High

234145

FADS1
Acyl-CoA

1

1

High-throughput

0.536

High

240912

S19A2
Thiamine transporter 1

1

1

High-throughput

0.536

High

326208

TSN15
Tetraspanin-15

1

6

High-throughput

0.536

High

518479

ADT3
ADP/ATP translocase 3

1

7

High-throughput

0.536

High

619284

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

2

High-throughput

0.536

High

708360

TTK
Dual specificity protein kinase TTK

1

3

High-throughput

0.536

High

839413

S26A2
Sulfate transporter

1

4

High-throughput

0.536

High

854910

CTR2
Cationic amino acid transporter 2

1

4

High-throughput

0.536

High

958369

AT8B2
Phospholipid-transporting ATPase ID

1

5

High-throughput

0.536

High

970443

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

3

High-throughput

0.536

High

975013

CAV1
Caveolin-1

1

2

High-throughput

0.536

High

976759

TAP1
Antigen peptide transporter 1

1

6

High-throughput

0.536

High

1031607

ATM
Serine-protein kinase ATM

1

1

High-throughput

0.536

High

1040087

MTR1L
Melatonin-related receptor

1

2

High-throughput

0.536

High

1068076

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.536

High

1137745

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

2

High-throughput

0.536

High

1148001

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

1

High-throughput

0.536

High

1154557

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.536

High

1156220

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

1

8

High-throughput

0.536

High

1156775

MFS12
Major facilitator superfamily domain-containing protein 12

1

1

High-throughput

0.536

High

1166784

MIC27
MICOS complex subunit MIC27

1

1

High-throughput

0.536

High

1201325

S2542
Mitochondrial coenzyme A transporter SLC25A42

1

8

High-throughput

0.536

High

1216925

T126B
Complex I assembly factor TMEM126B, mitochondrial

1

1

High-throughput

0.536

High

1217798

ZDH21
Palmitoyltransferase ZDHHC21

1

2

High-throughput

0.536

High

1230222

ORML3
ORM1-like protein 3

1

6

High-throughput

0.536

High

1240104

TM87A
Transmembrane protein 87A

1

1

High-throughput

0.536

High

1242809

T161B
Transmembrane protein 161B

1

1

High-throughput

0.536

High

1250927

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

2

High-throughput

0.536

High

1253076

S2540
Mitochondrial glutathione transporter SLC25A40

1

8

High-throughput

0.536

High

1253831

SPPL3
Signal peptide peptidase-like 3

1

3

High-throughput

0.536

High

1254426

SFXN5
Sideroflexin-5

1

2

High-throughput

0.536

High

1264245

CTR3
Cationic amino acid transporter 3

1

5

High-throughput

0.536

High

1266499

YLAT2
Y+L amino acid transporter 2

1

5

High-throughput

0.536

High

1283935

S2546
Mitochondrial outer membrane protein SLC25A46

1

5

High-throughput

0.536

High

1287783

ORAI1
Calcium release-activated calcium channel protein 1

1

1

High-throughput

0.536

High

1313426

SCMC3
Mitochondrial adenyl nucleotide antiporter SLC25A23

1

8

High-throughput

0.536

High

1314781

SFXN3
Sideroflexin-3

1

2

High-throughput

0.536

High

1315106

SGPP1
Sphingosine-1-phosphate phosphatase 1

1

2

High-throughput

0.536

High

1325966

YIPF3
Protein YIPF3

1

1

High-throughput

0.536

High

1327038

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

10

High-throughput

0.536

High

1327046

AT133
Polyamine-transporting ATPase 13A3

1

4

High-throughput

0.536

High

1327051

RTN4
Reticulon-4

1

3

High-throughput

0.536

High

1327053

SERC1
Serine incorporator 1

1

2

High-throughput

0.536

High

1327055

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

3

High-throughput

0.536

High

1327057

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

4

High-throughput

0.536

High

1327058

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

4

High-throughput

0.536

High

1327062

MTFP1
Mitochondrial fission process protein 1

1

1

High-throughput

0.536

High

1327063

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

2

High-throughput

0.536

High

1327064

NB5R1
NADH-cytochrome b5 reductase 1

1

1

High-throughput

0.536

High

1327067

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

3

High-throughput

0.536

High

1327075

ORNT1
Mitochondrial ornithine transporter 1

1

8

High-throughput

0.536

High

1327076

KC1G3
Casein kinase I isoform gamma-3

1

1

High-throughput

0.536

High

1132921

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

1

3

Small-scale

0.527

High

126856

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

159505

QCR8
Cytochrome b-c1 complex subunit 8

1

0

High-throughput

0.513

High

178765

STX7
Syntaxin-7

1

0

High-throughput

0.513

High

207105

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

262646

LAT3
Large neutral amino acids transporter small subunit 3

1

0

High-throughput

0.513

High

277452

DGAT1
Diacylglycerol O-acyltransferase 1

1

0

High-throughput

0.513

High

306424

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.513

High

306549

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

0

High-throughput

0.513

High

371106

NU1M
NADH-ubiquinone oxidoreductase chain 1

1

0

High-throughput

0.513

High

565404

TMM11
Transmembrane protein 11, mitochondrial

1

0

High-throughput

0.513

High

815816

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

0

High-throughput

0.513

High

839346

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.513

High

841520

KNTC1
Kinetochore-associated protein 1

1

0

High-throughput

0.513

High

1001263

NTCP7
Sodium/bile acid cotransporter 7

1

0

High-throughput

0.513

High

1040245

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.513

High

1049786

EFR3A
Protein EFR3 homolog A

1

0

High-throughput

0.513

High

1074651

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.513

High

1084171

OCLN
Occludin

1

0

High-throughput

0.513

High

1084766

TAZ
Tafazzin

1

0

High-throughput

0.513

High

1155918

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

0

High-throughput

0.513

High

1231942

GPD1L
Glycerol-3-phosphate dehydrogenase 1-like protein

1

0

High-throughput

0.513

High

1259749

ABHD3
Phospholipase ABHD3

1

0

High-throughput

0.513

High

1260290

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.513

High

1285976

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.513

High

1287987

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.513

High

1292118

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

1297455

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.513

High

1312333

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.513

High

1315303

TACAN
Ion channel TACAN

1

0

High-throughput

0.513

High

1326576

SRR
Serine racemase

1

0

High-throughput

0.513

High

1326883

COA1
Cytochrome c oxidase assembly factor 1 homolog

1

0

High-throughput

0.513

High

1327039

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.513

High

1327040

PIGU
Phosphatidylinositol glycan anchor biosynthesis class U protein

1

0

High-throughput

0.513

High

1327042

EMRE
Essential MCU regulator, mitochondrial

1

0

High-throughput

0.513

High

1327044

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.513

High

1327047

AGRL3
Adhesion G protein-coupled receptor L3

1

0

High-throughput

0.513

High

1327049

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

1

0

High-throughput

0.513

High

1327050

GPC5C
G-protein coupled receptor family C group 5 member C

1

0

High-throughput

0.513

High

1327065

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.513

High

1327069

SC5A6
Sodium-dependent multivitamin transporter

1

0

High-throughput

0.513

High

1327073

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.513

High

69687

HACD1
Very-long-chain

1

1

High-throughput

0.489

High

123405

GET1
Guided entry of tail-anchored proteins factor 1

1

1

High-throughput

0.489

High

212228

ERD23
ER lumen protein-retaining receptor 3

1

1

High-throughput

0.489

High

214789

PM34
Peroxisomal membrane protein PMP34

1

8

High-throughput

0.489

High

277579

DHRS3
Short-chain dehydrogenase/reductase 3

1

2

High-throughput

0.489

High

371188

NU4M
NADH-ubiquinone oxidoreductase chain 4

1

1

High-throughput

0.489

High

371240

NU5M
NADH-ubiquinone oxidoreductase chain 5

1

1

High-throughput

0.489

High

421270

GDN
Glia-derived nexin

1

1

High-throughput

0.489

High

444040

A2AP
Alpha-2-antiplasmin

1

2

High-throughput

0.489

High

882196

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

1

High-throughput

0.489

High

913407

SELT
Thioredoxin reductase-like selenoprotein T

1

1

High-throughput

0.489

High

1019264

TM115
Transmembrane protein 115

1

2

High-throughput

0.489

High

1037382

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.489

High

1108954

S2535
Solute carrier family 25 member 35

1

9

High-throughput

0.489

High

1120195

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

2

High-throughput

0.489

High

1120732

ORML2
ORM1-like protein 2

1

6

High-throughput

0.489

High

1124774

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

1

High-throughput

0.489

High

1126178

MTX3
Metaxin-3

1

4

High-throughput

0.489

High

1157272

ZNT6
Zinc transporter 6

1

2

High-throughput

0.489

High

1158210

MBOA5
Lysophospholipid acyltransferase 5

1

5

High-throughput

0.489

High

1167863

HACD2
Very-long-chain

1

1

High-throughput

0.489

High

1168256

CERS6
Ceramide synthase 6

1

2

High-throughput

0.489

High

1192623

PIGW
Phosphatidylinositol-glycan biosynthesis class W protein

1

3

High-throughput

0.489

High

1221315

S35F2
Solute carrier family 35 member F2

1

1

High-throughput

0.489

High

1236162

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

1

High-throughput

0.489

High

1237784

ARL10
ADP-ribosylation factor-like protein 10

1

1

High-throughput

0.489

High

1245953

MFSD8
Major facilitator superfamily domain-containing protein 8

1

6

High-throughput

0.489

High

1252083

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.489

High

1256708

PIGO
GPI ethanolamine phosphate transferase 3

1

1

High-throughput

0.489

High

1259791

SMAP2
Stromal membrane-associated protein 2

1

1

High-throughput

0.489

High

1272451

CDS1
Phosphatidate cytidylyltransferase 1

1

1

High-throughput

0.489

High

1288750

RSPRY
RING finger and SPRY domain-containing protein 1

1

1

High-throughput

0.489

High

1290329

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

1

High-throughput

0.489

High

1293430

CREL1
Protein disulfide isomerase CRELD1

1

1

High-throughput

0.489

High

1298164

TLCD4
TLC domain-containing protein 4

1

2

High-throughput

0.489

High

1298476

MBOA7
Lysophospholipid acyltransferase 7

1

5

High-throughput

0.489

High

1301214

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

4

High-throughput

0.489

High

1302287

DIRC2
Solute carrier family 49 member 4

1

3

High-throughput

0.489

High

1313318

RCAF1
GEL complex subunit OPTI

1

1

High-throughput

0.489

High

1313949

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

2

High-throughput

0.489

High

1326094

DERL2
Derlin-2

1

1

High-throughput

0.489

High

1326684

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

2

High-throughput

0.489

High

1327052

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.489

High

1327054

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

3

High-throughput

0.489

High

1327059

ELOV2
Very long chain fatty acid elongase 2

1

2

High-throughput

0.489

High

1327060

ORML1
ORM1-like protein 1

1

6

High-throughput

0.489

High

1327068

CDYL
Chromodomain Y-like protein

1

1

High-throughput

0.489

High

1327071

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.489

High

120628

RHOD
Rho-related GTP-binding protein RhoD

1

10

High-throughput

0.479

High

349629

RASH
GTPase HRas

1

1

High-throughput

0.479

High

436495

RHOC
Rho-related GTP-binding protein RhoC

1

8

High-throughput

0.479

High

545603

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.479

High

852611

RND2
Rho-related GTP-binding protein RhoN

1

10

High-throughput

0.479

High

892583

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

High-throughput

0.479

High

894403

CDC42
Cell division control protein 42 homolog

1

7

High-throughput

0.479

High

900876

RHOA
Transforming protein RhoA

1

9

High-throughput

0.479

High

915956

RHOB
Rho-related GTP-binding protein RhoB

1

9

High-throughput

0.479

High

925597

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

High-throughput

0.479

High

951314

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

1076746

RHOH
Rho-related GTP-binding protein RhoH

1

9

High-throughput

0.479

High

1183542

RHOU
Rho-related GTP-binding protein RhoU

1

7

High-throughput

0.479

High

1327041

Q9H4D1
Protein kinase

1

1

High-throughput

0.479

High

1327048

RHOF
Rho-related GTP-binding protein RhoF

1

10

High-throughput

0.479

High

1302641

Q96T11
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to ANKYRIN R

1

1

High-throughput

0.445

High

474538

GPHRB
Golgi pH regulator B

1

3

High-throughput

0.437

High

81842

GPHRA
Golgi pH regulator A

1

3

High-throughput

0.407

High

64446

RTL8C
Retrotransposon Gag-like protein 8C

1

0

High-throughput

0.279

Low

135749

EST2
Cocaine esterase

1

0

High-throughput

0.279

Low

781694

EIF2D
Eukaryotic translation initiation factor 2D

1

0

High-throughput

0.279

Low

880442

ATP68
ATP synthase subunit ATP5MJ, mitochondrial

1

0

High-throughput

0.279

Low

1058877

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.279

Low

1121875

TM177
Transmembrane protein 177

1

0

High-throughput

0.279

Low

1166199

DHR13
Dehydrogenase/reductase SDR family member 13

1

0

High-throughput

0.279

Low

1167223

PACS1
Phosphofurin acidic cluster sorting protein 1

1

0

High-throughput

0.279

Low

1201062

PNM8A
Paraneoplastic antigen-like protein 8A

1

0

High-throughput

0.279

Low

1216759

TPPC5
Trafficking protein particle complex subunit 5

1

0

High-throughput

0.279

Low

1255065

DMXL2
DmX-like protein 2

1

0

High-throughput

0.279

Low

1269067

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

0

High-throughput

0.279

Low

1294656

ABHEB
Putative protein-lysine deacylase ABHD14B

1

0

High-throughput

0.279

Low

1295146

VPS50
Syndetin

1

0

High-throughput

0.279

Low

1309344

CYBC1
Cytochrome b-245 chaperone 1

1

0

High-throughput

0.279

Low

1311313

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.279

Low

1313824

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.279

Low

1313841

PHF20
PHD finger protein 20

1

0

High-throughput

0.279

Low

1315249

5NT1A
Cytosolic 5'-nucleotidase 1A

1

0

High-throughput

0.279

Low

1326665

CF062
Uncharacterized protein C6orf62

1

0

High-throughput

0.279

Low

1327043

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.279

Low

1327045

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.279

Low

1327056

SNTG1
Gamma-1-syntrophin

1

0

High-throughput

0.279

Low

1327061

B4GT7
Beta-1,4-galactosyltransferase 7

1

0

High-throughput

0.279

Low

1327066

DOLK
Dolichol kinase

1

0

High-throughput

0.279

Low

1327070

KLDC2
Kelch domain-containing protein 2

1

0

High-throughput

0.279

Low

1327072

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

1327074

TPPC1
Trafficking protein particle complex subunit 1

1

0

High-throughput

0.279

Low

456644

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024