HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	24722339, 36089195, 11850410, 12626569
Identification Methods	pull down, proximity labelling technology, affinity chromatography technology, enzymatic study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 488
+	Hs
		1086250 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		952512 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		934735 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038423 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		952319 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		111560 K7EK07_HUMAN (1-132): 2.4e-59: 181: 96.21		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		828220 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	At
		886469 H33_ARATH (1-136): 7.67e-62: 187: 96.32		HDA6_ARATH (1-467): 0: 578: 57.02
+	Hs
		177255 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		952773 H33_MOUSE (1-136): 2.73e-61: 186: 96.32		Q9JM08_MOUSE (10-431): 0: 568: 58.02
+	Sc
		693050 H3_YEAST (1-136): 1.16e-55: 172: 88.97		RPD3_YEAST (5-422): 0: 577: 60.95
+	Ce
		184839 HCP3_CAEEL (11-131): 9.69e-45: 149: 48.39		HDA1_CAEEL (7-456): 0: 595: 64.02
+	Sp
		140575 H31_SCHPO (1-136): 3.54e-59: 181: 91.91		PHD1_SCHPO (7-411): 0: 519: 52.56
+	Sc
		859059 H3_YEAST (1-136): 1.16e-55: 172: 88.97		HOS2_YEAST (11-430): 5.02e-174: 498: 47.18
+	Hs
		935199 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		HDAC8_HUMAN (33-372): 1.01e-137: 403: 43.40
+	Hs
		1086303 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		HDAC8_HUMAN (33-372): 1.01e-137: 403: 43.40
+	Sc
		866875 H3_YEAST (1-136): 1.16e-55: 172: 88.97		HDA1_YEAST (9-330): 1.24e-121: 373: 27.56
+	Hs
		935331 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04