Protein: PEX6
Peroxisomal ATPase PEX6 (EC 3.6.4.-) (Peroxin-6) (Peroxisomal biogenesis factor 6) (Peroxisomal-type ATPase 1) (Peroxisome assembly factor 2) (PAF-2)

Gene: PEX6
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q13608

Gene Ontology (top 5):
GO:0001750 - photoreceptor outer segment
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

610320

PRS6A
26S proteasome regulatory subunit 6A

3

20

High-throughput

0.861

High

231699

PEX1
Peroxisomal ATPase PEX1

2

17

Small-scale

0.821

High

1112247

PEX26
Peroxisome assembly protein 26

3

1

Small-scale

0.664

High

350706

NOE2
Noelin-2

2

1

High-throughput

0.628

High

635314

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

2

1

High-throughput

0.628

High

639727

TAF1
Transcription initiation factor TFIID subunit 1

1

12

High-throughput

0.618

High

888454

TSP3
Thrombospondin-3

3

2

High-throughput

0.609

High

1112249

TMM25
Transmembrane protein 25

3

2

High-throughput

0.609

High

1112268

KBTB4
Kelch repeat and BTB domain-containing protein 4

2

4

High-throughput

0.574

High

1112274

DKKL1
Dickkopf-like protein 1

2

3

High-throughput

0.574

High

342175

BRD1
Bromodomain-containing protein 1

1

7

High-throughput

0.553

High

858916

RL27A
Large ribosomal subunit protein uL15

1

3

High-throughput

0.541

High

972393

RS14
Small ribosomal subunit protein uS11

1

4

High-throughput

0.541

High

64866

RCCD1
RCC1 domain-containing protein 1

1

7

High-throughput

0.536

High

260755

RAMP2
Receptor activity-modifying protein 2

1

1

High-throughput

0.536

High

334184

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

6

High-throughput

0.536

High

445176

S10A6
Protein S100-A6

1

4

High-throughput

0.536

High

457419

TBB5
Tubulin beta chain

1

7

High-throughput

0.536

High

549585

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

4

High-throughput

0.536

High

983790

RBX1
E3 ubiquitin-protein ligase RBX1

1

5

High-throughput

0.536

High

1064567

HDHD1
Pseudouridine-5'-phosphatase

1

2

High-throughput

0.536

High

1112239

PTC1
Protein patched homolog 1

1

2

High-throughput

0.536

High

1112240

SF3B3
Splicing factor 3B subunit 3

1

2

High-throughput

0.536

High

1112248

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

1

High-throughput

0.536

High

1112260

FBXW5
F-box/WD repeat-containing protein 5

1

1

High-throughput

0.536

High

1112264

TCPQM
T-complex protein 1 subunit theta-like 2

1

12

High-throughput

0.536

High

1112266

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

3

High-throughput

0.536

High

1112271

KLH14
Kelch-like protein 14

1

3

High-throughput

0.536

High

1112275

CLC11
C-type lectin domain family 11 member A

1

2

High-throughput

0.536

High

1112276

KLK5
Kallikrein-5

1

1

High-throughput

0.536

High

226976

ENSA
Alpha-endosulfine

1

0

High-throughput

0.513

High

289773

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.513

High

296773

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

655992

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.513

High

1006245

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.513

High

1054580

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

1089089

OVGP1
Oviduct-specific glycoprotein

1

0

High-throughput

0.513

High

1112244

SWAP1
ATPase SWSAP1

1

0

High-throughput

0.513

High

896234

PEX5
Peroxisomal targeting signal 1 receptor

1

5

Small-scale

0.501

High

1112261

CERS2
Ceramide synthase 2

1

1

High-throughput

0.494

High

74484

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

3

High-throughput

0.489

High

260863

RAMP3
Receptor activity-modifying protein 3

1

1

High-throughput

0.489

High

261495

B4GT2
Beta-1,4-galactosyltransferase 2

1

1

High-throughput

0.489

High

366411

FA12
Coagulation factor XII

1

1

High-throughput

0.489

High

1041987

LMNB2
Lamin-B2

1

11

High-throughput

0.489

High

1112241

INF2
Inverted formin-2

1

5

High-throughput

0.489

High

1112250

KLH34
Kelch-like protein 34

1

3

High-throughput

0.489

High

1112253

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

1

High-throughput

0.489

High

1112255

F174A
Membrane protein FAM174A

1

3

High-throughput

0.489

High

1112256

HUMMR
Protein MGARP

1

1

High-throughput

0.489

High

1112257

NPRL2
GATOR1 complex protein NPRL2

1

2

High-throughput

0.489

High

1112258

HPSE2
Inactive heparanase-2

1

1

High-throughput

0.489

High

1112262

PPM1M
Protein phosphatase 1M

1

1

High-throughput

0.489

High

1112265

NPAS1
Neuronal PAS domain-containing protein 1

1

2

High-throughput

0.489

High

1112278

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.489

High

1112279

EMIL1
EMILIN-1

1

4

High-throughput

0.489

High

278856

PEX14
Peroxisomal membrane protein PEX14

1

2

High-throughput

0.479

High

659223

SP100
Nuclear autoantigen Sp-100

1

4

High-throughput

0.479

High

901227

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.479

High

941899

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.479

High

1112238

CUL3
Cullin-3

1

12

High-throughput

0.479

High

1112254

LNX1
E3 ubiquitin-protein ligase LNX

1

2

Small-scale

0.479

High

1112259

AKAP1
A-kinase anchor protein 1, mitochondrial

1

6

High-throughput

0.479

High

1112267

PXMP2
Peroxisomal membrane protein 2

1

2

High-throughput

0.479

High

1112273

XPO7
Exportin-7

1

7

High-throughput

0.479

High

1112277

FIS1
Mitochondrial fission 1 protein

1

2

High-throughput

0.479

High

1112245

MCAF1
Activating transcription factor 7-interacting protein 1

1

4

High-throughput

0.457

High

231570

PRKY
Putative serine/threonine-protein kinase PRKY

1

6

High-throughput

0.445

High

563729

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.445

High

1112269

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.437

High

1112270

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

2

High-throughput

0.437

High

516918

CB27B
Putative uncharacterized protein CDRT15P3

1

1

High-throughput

0.407

High

906274

GPC3
Glypican-3

1

1

High-throughput

0.407

High

1112242

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

2

High-throughput

0.407

High

1112246

PKHG7
Pleckstrin homology domain-containing family G member 7

1

3

High-throughput

0.407

High

1112272

SL9A2
Sodium/hydrogen exchanger 2

1

1

High-throughput

0.407

High

549769

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.328

High

465845

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.279

Low

596480

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

1112243

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.279

Low

1112252

FA83F
Protein FAM83F

1

0

High-throughput

0.279

Low

1112263

YI001
Uncharacterized protein FLJ30774

1

0

High-throughput

0.249

Low

1112251

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025