Interactor 1: APC (P70478)
Adenomatous polyposis coli protein (Protein APC)
Gene: APC

Interactor 2: CTNB1 (Q9WU82)
Catenin beta-1 (Beta-catenin)
Gene: Ctnnb1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.817

The method score is based on:

Property Details
Experiments 20623542, 16815997, 10947987
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains APC_15aa~Arm, APC_rep~Arm, Arm~Arm
Common GO terms GO:0000165 - MAPK cascade
GO:0001708 - cell fate specification
GO:0001822 - kidney development
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 36 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2842
Rn

1 781
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024