HitPredict

Interactor 1: IRF3 (P70671)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Interactor 2: IRF3 (P70671)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 19426678, 24696485, 19805092, 19890330
Identification Methods comigration in non denaturing gel electrophoresis, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRF~IRF, IRF-3~IRF-3
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001819 - positive regulation of cytokine production
and 29 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 419
Mm

1 419
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024