HitPredict

Interactor 1: F1LST4 (F1LST4)
Microtubule-associated protein
Gene: Mapt

Interactor 2: NFL (P19527)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: Nefl

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32357304
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005829 - cytosol GO:0030424 - axon
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 775 Rn			1 542
+	Rn
		581922 TAU_RAT (1-751): 2.82e-89: 299: 99.87		NFL_RAT (1-542): 6.14e-151: 445: 100.00
+	Hs
		422133 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		NFL_HUMAN (1-542): 1.13e-145: 431: 91.73
+	Rn
		94148 F1LST4_RAT (1-775): 1.56e-96: 318: 100.00		AINX_RAT (65-536): 8.1e-83: 268: 46.62
+	Rn
		581925 TAU_RAT (1-751): 2.82e-89: 299: 99.87		AINX_RAT (65-536): 8.1e-83: 268: 46.62
+	Rn
		94135 F1LST4_RAT (1-775): 1.56e-96: 318: 100.00		NFM_RAT (27-470): 7.09e-73: 249: 45.86
+	Hs
		422135 MTAP2_HUMAN (37-751): 1.21e-31: 135: 24.00		NFL_HUMAN (1-542): 1.13e-145: 431: 91.73
+	Rn
		522304 TAU_RAT (1-751): 2.82e-89: 299: 99.87		NFM_RAT (27-470): 7.09e-73: 249: 45.86
+	Rn
		94169 F1LST4_RAT (1-775): 1.56e-96: 318: 100.00		GFAP_RAT (23-402): 2.84e-66: 223: 45.00
+	Rn
		581945 TAU_RAT (1-751): 2.82e-89: 299: 99.87		GFAP_RAT (23-402): 2.84e-66: 223: 45.00
+	Mm
		440283 TAU_MOUSE (1-751): 2.06e-76: 263: 89.51		NFM_MOUSE (27-481): 8.31e-72: 247: 45.42
+	Hs
		497096 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		AINX_HUMAN (66-536): 4.31e-86: 276: 47.15
+	Hs
		443287 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		VIME_HUMAN (34-403): 1.51e-82: 266: 50.00
+	Mm
		372929 TAU_MOUSE (1-751): 2.06e-76: 263: 89.51		GFAP_MOUSE (66-402): 8.22e-67: 224: 47.48
+	Hs
		422332 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		NFM_HUMAN (82-410): 8.09e-73: 251: 54.71
+	Hs
		496488 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		PERI_HUMAN (9-402): 4.39e-70: 234: 47.87
+	Hs
		496206 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		GFAP_HUMAN (66-402): 4.23e-69: 230: 48.37
+	Hs
		496199 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		K2C5_HUMAN (55-510): 1.39e-66: 228: 25.98
+	Hs
		359457 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		K2C6A_HUMAN (55-420): 5.44e-65: 223: 30.98
+	Hs
		203200 SYNJ1_HUMAN (306-748): 1.26e-12: 73.9: 13.11		VIME_HUMAN (34-403): 1.51e-82: 266: 50.00
+	Hs
		203211 SYNJ1_HUMAN (306-748): 1.26e-12: 73.9: 13.11		PERI_HUMAN (9-402): 4.39e-70: 234: 47.87