HitPredict

Interactor 1: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: NMDE1 (Q12879)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A) (hNR2A)
Gene: GRIN2A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.764

The method score is based on:

Property Details
Experiments 17459877, 18400955, 12419528, 9278515, 9286858, 23183381, 21653829, 11937501, 14732708, 22375001, 16332682, 10648730, 20869595, 14529713, 25143613, 8601796, 17360663
Identification Methods affinity chromatography technology, pull down, two hybrid, unspecified method, far western blotting, anti bait coimmunoprecipitation, two hybrid pooling approach, fluorescence polarization spectroscopy, enzyme linked immunosorbent assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
GO:0008021 - synaptic vesicle
GO:0014069 - postsynaptic density
GO:0043197 - dendritic spine
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 724
Hs

1 1464
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Last updated: 15 Jul 2024