HitPredict

Interactor 1: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: FZD2 (Q14332)
Frizzled-2 (Fz-2) (hFz2) (FzE2)
Gene: FZD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	12067714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 565
+	Mm
		1143526 DLG4_MOUSE (1-724): 0: 667: 99.59		FZD2_MOUSE (1-565): 0: 781: 98.60
+	Hs
		254162 DLG4_HUMAN (1-724): 0: 667: 100.00		FZD7_HUMAN (23-565): 0: 774: 79.56
+	Mm
		1142150 DLG4_MOUSE (1-724): 0: 667: 99.59		FZD7_MOUSE (20-565): 0: 768: 78.98
+	Hs
		942398 DLG4_HUMAN (1-724): 0: 667: 100.00		FZD1_HUMAN (25-565): 0: 768: 79.38
+	Mm
		250809 DLG4_MOUSE (1-724): 0: 667: 99.59		FZD1_MOUSE (25-565): 0: 762: 79.02
+	Hs
		942397 DLG4_HUMAN (1-724): 0: 667: 100.00		FZD4_HUMAN (28-560): 0: 602: 44.49
+	Mm
		1142145 DLG4_MOUSE (1-724): 0: 667: 99.59		FZD4_MOUSE (30-560): 0: 598: 44.28
+	Mm
		1142152 DLG1_MOUSE (147-465): 2.02e-19: 95.5: 18.54		FZD7_MOUSE (20-565): 0: 768: 78.98
+	Mm
		1142153 DLG2_MOUSE (225-474): 1.48e-18: 92.5: 21.09		FZD7_MOUSE (20-565): 0: 768: 78.98
+	Mm
		250810 DLG1_MOUSE (147-465): 2.02e-19: 95.5: 18.54		FZD1_MOUSE (25-565): 0: 762: 79.02
+	Mm
		250811 DLG2_MOUSE (225-474): 1.48e-18: 92.5: 21.09		FZD1_MOUSE (25-565): 0: 762: 79.02
+	Mm
		1142147 DLG1_MOUSE (147-465): 2.02e-19: 95.5: 18.54		FZD4_MOUSE (30-560): 0: 598: 44.28
+	Mm
		1142148 DLG2_MOUSE (225-474): 1.48e-18: 92.5: 21.09		FZD4_MOUSE (30-560): 0: 598: 44.28