HitPredict

Interactor 1: F1LW22 (F1LW22)
Par-3 family cell polarity regulator beta
Gene: Pard3b

Interactor 2: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1093 Rn			1 1383
+	Hs
		872464 PARD3_HUMAN (1-1089): 5.52e-121: 405: 35.43		EPHA5_HUMAN (662-1320): 0: 581: 24.11
+	Hs
		872679 PARD3_HUMAN (1-1089): 5.52e-121: 405: 35.43		EPHA4_HUMAN (662-1328): 0: 570: 24.19
+	Hs
		1072560 PARD3_HUMAN (1-1089): 5.52e-121: 405: 35.43		EPHA7_HUMAN (664-1321): 0: 568: 22.55
+	Hs
		665414 PARD3_HUMAN (1-1089): 5.52e-121: 405: 35.43		EPHA3_HUMAN (661-1320): 4.01e-172: 541: 24.15
+	Hs
		665294 PARD3_HUMAN (1-1089): 5.52e-121: 405: 35.43		EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70
+	Hs
		872433 DLG1_HUMAN (80-660): 1.83e-53: 204: 13.79		EPHA5_HUMAN (662-1320): 0: 581: 24.11
+	Hs
		872639 DLG1_HUMAN (80-660): 1.83e-53: 204: 13.79		EPHA4_HUMAN (662-1328): 0: 570: 24.19
+	Hs
		1021499 DLG1_HUMAN (80-660): 1.83e-53: 204: 13.79		EPHA7_HUMAN (664-1321): 0: 568: 22.55
+	Hs
		1083872 PARD3_HUMAN (1-1089): 5.52e-121: 405: 35.43		NTRK2_HUMAN (997-1293): 1.8e-67: 246: 42.72
+	Hs
		1081544 PARD3_HUMAN (1-1089): 5.52e-121: 405: 35.43		NTRK3_HUMAN (997-1291): 5.26e-62: 230: 38.80
+	Hs
		338738 PARD3_HUMAN (1-1089): 5.52e-121: 405: 35.43		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		942352 DLG4_HUMAN (63-680): 6e-69: 247: 16.82		NTRK2_HUMAN (997-1293): 1.8e-67: 246: 42.72
+	Mm
		546303 DLG4_MOUSE (63-680): 7.21e-69: 247: 16.67		NTRK2_MOUSE (997-1293): 1.64e-66: 244: 42.38
+	Hs
		384746 DLG1_HUMAN (80-660): 1.83e-53: 204: 13.79		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		1021503 DLG1_HUMAN (80-660): 1.83e-53: 204: 13.79		NTRK3_HUMAN (997-1291): 5.26e-62: 230: 38.80
+	Hs
		942346 DLG4_HUMAN (63-680): 6e-69: 247: 16.82		ERBB4_HUMAN (44-347): 2.97e-26: 119: 20.42
+	Mm
		1142638 DLG4_MOUSE (63-680): 7.21e-69: 247: 16.67		ERBB4_MOUSE (44-347): 9.25e-26: 117: 20.42
+	Hs
		383736 DLG4_HUMAN (63-680): 6e-69: 247: 16.82		ERBB2_HUMAN (32-342): 4.75e-18: 92.8: 19.83
+	Hs
		1021496 DLG1_HUMAN (80-660): 1.83e-53: 204: 13.79		ERBB4_HUMAN (44-347): 2.97e-26: 119: 20.42
+	Hs
		1070968 DLG2_HUMAN (306-925): 7.65e-51: 196: 15.69		ERBB4_HUMAN (44-347): 2.97e-26: 119: 20.42