HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26949739, 35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 768
+	Hs
		1042381 TCPH_HUMAN (4-532): 0: 591: 34.08		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		826653 TCPG_HUMAN (3-532): 0: 561: 28.33		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		573253 TCPA_HUMAN (5-533): 0: 541: 34.30		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		821202 TCPE_HUMAN (1-528): 0: 541: 32.29		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		821203 TCPE_HUMAN (1-528): 0: 541: 32.29		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		943221 TCPB_HUMAN (1-535): 0: 586: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Sp
		251317 TCPG_SCHPO (5-526): 0: 559: 26.74		CUL3_SCHPO (11-768): 0: 648: 37.04