HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: PTK6 (Q13882)
Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)
Gene: PTK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 451
+	Hs
		412325 TCPH_HUMAN (4-532): 0: 591: 34.08		FYN_HUMAN (10-450): 0: 521: 42.35
+	Hs
		411833 TCPH_HUMAN (4-532): 0: 591: 34.08		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		412130 TCPB_HUMAN (1-535): 0: 586: 100.00		FYN_HUMAN (10-450): 0: 521: 42.35
+	Hs
		433319 TCPB_HUMAN (1-535): 0: 586: 100.00		YES_HUMAN (10-450): 0: 519: 42.86
+	Hs
		411670 TCPB_HUMAN (1-535): 0: 586: 100.00		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		454845 TCPH_HUMAN (4-532): 0: 591: 34.08		FGR_HUMAN (10-450): 3.32e-177: 508: 42.41
+	Hs
		454821 TCPB_HUMAN (1-535): 0: 586: 100.00		FGR_HUMAN (10-450): 3.32e-177: 508: 42.41
+	Hs
		1046418 TCPH_HUMAN (4-532): 0: 591: 34.08		PTK6_HUMAN (1-451): 2.09e-175: 500: 100.00
+	Hs
		412086 TCPG_HUMAN (3-532): 0: 561: 28.33		FYN_HUMAN (10-450): 0: 521: 42.35
+	Hs
		433290 TCPG_HUMAN (3-532): 0: 561: 28.33		YES_HUMAN (10-450): 0: 519: 42.86
+	Hs
		411642 TCPG_HUMAN (3-532): 0: 561: 28.33		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		846519 TCPH_HUMAN (4-532): 0: 591: 34.08		BLK_HUMAN (7-449): 2e-169: 487: 39.51
+	Hs
		846458 TCPB_HUMAN (1-535): 0: 586: 100.00		BLK_HUMAN (7-449): 2e-169: 487: 39.51
+	Hs
		454809 TCPG_HUMAN (3-532): 0: 561: 28.33		FGR_HUMAN (10-450): 3.32e-177: 508: 42.41
+	Hs
		412084 TCPE_HUMAN (1-528): 0: 541: 32.29		FYN_HUMAN (10-450): 0: 521: 42.35
+	Hs
		826655 TCPG_HUMAN (3-532): 0: 561: 28.33		PTK6_HUMAN (1-451): 2.09e-175: 500: 100.00
+	Hs
		411639 TCPE_HUMAN (1-528): 0: 541: 32.29		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		454808 TCPE_HUMAN (1-528): 0: 541: 32.29		FGR_HUMAN (10-450): 3.32e-177: 508: 42.41
+	Hs
		826575 TCPG_HUMAN (3-532): 0: 561: 28.33		BLK_HUMAN (7-449): 2e-169: 487: 39.51
+	Hs
		826630 TCPG_HUMAN (3-532): 0: 561: 28.33		ITK_HUMAN (7-447): 1.9e-152: 448: 32.82