HitPredict

Interactor 1: RAE1L (P78406)
mRNA export factor RAE1 (Rae1 protein homolog) (mRNA-associated protein mrnp 41)
Gene: RAE1

Interactor 2: WDR24 (Q96S15)
GATOR2 complex protein WDR24 (EC 2.3.2.27) (WD repeat-containing protein 24)
Gene: WDR24

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	19615732
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 368 Hs			1 790
+	Hs
		943852 RAE1L_HUMAN (1-368): 5.99e-98: 296: 100.00		WDR59_HUMAN (159-345): 6.31e-21: 100: 20.31
+	Ce
		954053 RAE1_CAEEL (2-368): 4.91e-82: 256: 49.87		LIN53_CAEEL (119-328): 1.62e-33: 135: 22.12
+	Hs
		943879 RAE1L_HUMAN (1-368): 5.99e-98: 296: 100.00		FBXW7_HUMAN (1-144): 3.38e-18: 91.4: 13.70
+	Hs
		943909 RAE1L_HUMAN (1-368): 5.99e-98: 296: 100.00		MIOS_HUMAN (2-326): 4.54e-17: 87.9: 13.22
+	Hs
		1240442 POC1B_HUMAN (2-159): 3.19e-39: 147: 21.30		POC1A_HUMAN (1-281): 4.63e-64: 221: 16.73
+	Hs
		792949 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		LIS1_HUMAN (2-284): 6.34e-64: 221: 13.91
+	Sp
		999838 TUP11_SCHPO (67-366): 2.41e-66: 222: 12.96		TUP11_SCHPO (1-108): 4.42e-12: 71.8: 13.56
+	Hs
		903204 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		PWP1_HUMAN (75-320): 2.56e-49: 183: 26.00
+	Hs
		1309163 TBL1R_HUMAN (2-160): 3.97e-41: 152: 17.71		TBL1Y_HUMAN (282-559): 5.29e-28: 121: 12.83
+	Hs
		245633 TBL1R_HUMAN (2-160): 3.97e-41: 152: 17.71		TBL1X_HUMAN (286-559): 4.64e-27: 118: 11.67
+	Hs
		245630 TBL1X_HUMAN (2-160): 2.62e-39: 148: 17.14		TBL1Y_HUMAN (282-559): 5.29e-28: 121: 12.83
+	Hs
		245546 TBL1X_HUMAN (2-160): 2.62e-39: 148: 17.14		TBL1X_HUMAN (286-559): 4.64e-27: 118: 11.67
+	Hs
		1162302 TBL1R_HUMAN (2-160): 3.97e-41: 152: 17.71		WDR59_HUMAN (159-345): 6.31e-21: 100: 20.31
+	Hs
		245613 TBL1X_HUMAN (2-160): 2.62e-39: 148: 17.14		WDR59_HUMAN (159-345): 6.31e-21: 100: 20.31
+	Sc
		630844 NLE1_YEAST (117-366): 6.81e-45: 163: 9.40		NLE1_YEAST (332-538): 1.04e-13: 76.3: 8.48
+	Hs
		1346954 NLE1_HUMAN (252-366): 5.64e-25: 107: 15.39		NLE1_HUMAN (280-564): 1.09e-27: 119: 10.36
+	Sp
		999842 TUP12_SCHPO (202-366): 2.53e-26: 111: 13.33		TUP11_SCHPO (1-108): 4.42e-12: 71.8: 13.56
+	Hs
		903551 NLE1_HUMAN (252-366): 5.64e-25: 107: 15.39		WDR5_HUMAN (1-102): 2.39e-12: 71: 14.42
+	Hs
		903077 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		WDR5_HUMAN (1-102): 2.39e-12: 71: 14.42