Protein: SOCS7
Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4)

Gene: SOCS7
Organism: Homo sapiens
Interactions: 42
UniProt ID: O14512

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008286 - insulin receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

155175

CUL5
Cullin-5

5

20

Small-scale

0.927

High

155147

VINEX
Vinexin

3

17

Small-scale

0.864

High

155152

NCK1
SH2/SH3 adapter protein NCK1

3

20

Small-scale

0.858

High

155146

NCK2
Cytoplasmic protein NCK2

3

20

High-throughput

0.858

High

155149

SRBS2
Sorbin and SH3 domain-containing protein 2

2

20

High-throughput

0.783

High

155151

YES
Tyrosine-protein kinase Yes

2

20

High-throughput

0.783

High

155157

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.783

High

155163

TENS2
Tensin-2

2

8

High-throughput

0.783

High

155154

STAT3
Signal transducer and activator of transcription 3

1

18

Small-scale

0.740

High

155179

KPCD2
Serine/threonine-protein kinase D2

1

10

High-throughput

0.691

High

155169

ABI1
Abl interactor 1

1

15

Small-scale

0.647

High

155166

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

14

High-throughput

0.621

High

155174

OSTF1
Osteoclast-stimulating factor 1

1

18

High-throughput

0.621

High

155145

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

20

Small-scale

0.618

High

155150

INSR
Insulin receptor

1

20

Small-scale

0.618

High

155155

STA5A
Signal transducer and activator of transcription 5A

1

18

Small-scale

0.618

High

155161

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

15

Small-scale

0.618

High

155171

GA2L2
GAS2-like protein 2

2

1

High-throughput

0.606

High

155178

MDFI
MyoD family inhibitor

2

1

High-throughput

0.606

High

155183

HSPB8
Heat shock protein beta-8

2

2

High-throughput

0.606

High

155164

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

2

0

High-throughput

0.580

High

155168

MISP
Mitotic interactor and substrate of PLK1

2

0

High-throughput

0.580

High

155176

EXOS8
Exosome complex component RRP43

2

0

High-throughput

0.580

High

155177

LENG8
Leukocyte receptor cluster member 8

2

0

High-throughput

0.580

High

155148

DAB1
Disabled homolog 1

1

16

Small-scale

0.536

High

155160

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.536

High

155170

KBTB8
Kelch repeat and BTB domain-containing protein 8

1

5

High-throughput

0.536

High

155172

FAT3
Protocadherin Fat 3

1

12

High-throughput

0.536

High

155180

JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4

1

1

High-throughput

0.536

High

155181

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

8

High-throughput

0.536

High

155182

RBX2
RING-box protein 2

1

9

High-throughput

0.536

High

155184

CE164
Centrosomal protein of 164 kDa

1

4

High-throughput

0.536

High

155156

DCAF7
DDB1- and CUL4-associated factor 7

1

0

High-throughput

0.513

High

155158

SEPT6
Septin-6

1

2

Small-scale

0.506

High

155173

K0232
Uncharacterized protein KIAA0232

1

1

High-throughput

0.489

High

155185

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

1

High-throughput

0.489

High

155153

IRS1
Insulin receptor substrate 1

1

20

Small-scale

0.479

High

155159

ELOB
Elongin-B

1

10

High-throughput

0.479

High

155162

ELAV1
ELAV-like protein 1

1

0

Small-scale

0.458

High

70032

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

155165

XIRP1
Xin actin-binding repeat-containing protein 1

1

0

High-throughput

0.279

Low

155167

P3H3
Prolyl 3-hydroxylase 3

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025