HitPredict

Interactor 1: ACT6 (P83967)
Actin, indirect flight muscle (EC 3.6.4.-) (Actin-88F)
Gene: Act88F

Interactor 2: Q9VWR1 (Q9VWR1)
IP04855p
Gene: adf

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.80	0.587

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Dm			1 148
+	Hs
		618104 ACTBL_HUMAN (1-376): 0: 724: 88.83		COF1_HUMAN (1-142): 7.94e-43: 140: 24.85
+	Hs
		1122425 ACTBL_HUMAN (1-376): 0: 724: 88.83		TWF2_HUMAN (3-144): 1.02e-39: 138: 22.45
+	Dm
		501459 ACT5_DROME (1-376): 0: 613: 97.61		Q9VWR1_DROME (1-148): 5.01e-58: 179: 100.00
+	Dm
		501443 ACT5_DROME (1-376): 0: 613: 97.61		CADF_DROME (1-148): 3.21e-56: 174: 52.70
+	Dm
		799742 ACT6_DROME (1-376): 0: 610: 100.00		CADF_DROME (1-148): 3.21e-56: 174: 52.70
+	Hs
		891728 ACTB_HUMAN (3-376): 0: 610: 95.99		TWF1_HUMAN (3-144): 1.03e-41: 143: 21.77
+	Hs
		1092828 Q1KLZ0_HUMAN (3-376): 0: 610: 95.99		Q549N0_HUMAN (1-142): 3.04e-43: 142: 24.22
+	Hs
		891649 ACTB_HUMAN (3-376): 0: 610: 95.99		DEST_HUMAN (1-142): 3.05e-43: 142: 26.88
+	Hs
		891817 ACTB_HUMAN (3-376): 0: 610: 95.99		Q549N0_HUMAN (1-142): 3.04e-43: 142: 24.22
+	Hs
		892124 ACTB_HUMAN (3-376): 0: 610: 95.99		COF2_HUMAN (1-142): 3.04e-43: 142: 24.22
+	Hs
		894665 Q1KLZ0_HUMAN (3-376): 0: 610: 95.99		DEST_HUMAN (1-142): 3.05e-43: 142: 26.88
+	Mm
		578583 ACTB_MOUSE (3-376): 0: 610: 95.99		COF1_MOUSE (1-142): 5.08e-43: 141: 24.85
+	Rn
		799735 ACTB_RAT (3-376): 0: 610: 95.99		COF1_RAT (1-142): 6.6e-43: 141: 24.85
+	Hs
		618038 ACTB_HUMAN (3-376): 0: 610: 95.99		COF1_HUMAN (1-142): 7.94e-43: 140: 24.85
+	Hs
		618096 Q1KLZ0_HUMAN (3-376): 0: 610: 95.99		COF1_HUMAN (1-142): 7.94e-43: 140: 24.85
+	Hs
		618049 ACTG_HUMAN (3-376): 0: 609: 95.46		COF1_HUMAN (1-142): 7.94e-43: 140: 24.85
+	Hs
		891834 ACTB_HUMAN (3-376): 0: 610: 95.99		TWF2_HUMAN (3-144): 1.02e-39: 138: 22.45
+	Dm
		501533 ACT1_DROME (1-376): 0: 613: 96.01		TWF_DROME (3-141): 3.01e-35: 126: 21.53
+	Ce
		501473 ACT4_CAEEL (1-376): 0: 615: 95.21		ADF1_CAEEL (1-136): 4.72e-32: 114: 28.29
+	Hs
		891650 ACTB_HUMAN (3-376): 0: 610: 95.99		GMFB_HUMAN (7-142): 2.99e-29: 105: 19.29