HitPredict

Interactor 1: H4 (P84040)
Histone H4
Gene: His4

Interactor 2: SCM (Q9VHA0)
Polycomb protein Scm (Sex comb on midleg protein)
Gene: SCM

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.50	0.519

Property	Details
Experiments	17932512
Identification Methods	x-ray crystallography, pull down, isothermal titration calorimetry
Interaction Type	association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 103 Dm			1 877
+	Hs
		918153 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		SCML2_HUMAN (140-869): 0: 586: 29.86
+	Hs
		917753 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		LMBL3_HUMAN (272-874): 1.31e-134: 422: 17.78
+	Hs
		918192 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		LMBL1_HUMAN (271-853): 4.27e-104: 343: 15.26
+	Hs
		917704 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		LMBL2_HUMAN (164-717): 2.33e-58: 214: 16.55
+	Dm
		950413 H4_DROME (1-103): 2.46e-48: 150: 100.00		SMBT_DROME (158-564): 4.6e-57: 215: 19.11
+	Dm
		950403 H4_DROME (1-103): 2.46e-48: 150: 100.00		Q9VB52_DROME (64-391): 5.56e-54: 206: 25.53
+	Hs
		917562 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		PHC2_HUMAN (377-869): 1.02e-49: 191: 13.59
+	Hs
		917155 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		MBTD1_HUMAN (153-622): 1.53e-46: 178: 15.26
+	Hs
		917614 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		PHC3_HUMAN (559-869): 2.97e-38: 156: 15.67
+	Hs
		917467 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		SAMD1_HUMAN (678-869): 2.04e-33: 138: 18.37
+	Hs
		918096 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		SMBT1_HUMAN (160-274): 7.48e-25: 113: 36.21