HitPredict

Interactor 1: H2A (P84051)
Histone H2A
Gene: His2A

Interactor 2: ESC (Q24338)
Polycomb protein esc (Protein extra sex combs)
Gene: ESC

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24837194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005700 - polytene chromosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 124 Dm			1 425
+	Hs
		470457 H2A1_HUMAN (1-122): 3.27e-61: 185: 89.43		DAW1_HUMAN (92-425): 3.75e-73: 236: 12.78
+	Hs
		245612 H2A2A_HUMAN (1-122): 1.75e-61: 185: 89.43		TBL1X_HUMAN (1-315): 6.08e-60: 206: 11.59
+	Hs
		594860 H2A1D_HUMAN (1-122): 3.17e-61: 185: 88.62		FBXW7_HUMAN (1-239): 7.98e-39: 150: 11.07
+	Hs
		555386 H2AX_HUMAN (1-120): 6.84e-62: 187: 90.91		WDR5_HUMAN (255-425): 4.13e-28: 115: 10.98
+	Hs
		391631 H2A1B_HUMAN (1-122): 3.57e-61: 185: 88.62		WDR5_HUMAN (255-425): 4.13e-28: 115: 10.98
+	Hs
		1151367 H2A2A_HUMAN (1-122): 1.75e-61: 185: 89.43		SNR40_HUMAN (1-154): 1.49e-27: 114: 11.32
+	Sc
		392519 H2A2_YEAST (15-124): 5.28e-53: 164: 80.91		COPA_YEAST (206-423): 2.07e-31: 129: 12.79
+	Hs
		267738 H2AX_HUMAN (1-120): 6.84e-62: 187: 90.91		TAF5L_HUMAN (108-422): 6.63e-15: 78.7: 15.34
+	Hs
		792998 H2A2A_HUMAN (1-122): 1.75e-61: 185: 89.43		LIS1_HUMAN (313-425): 1.52e-15: 79.8: 14.16
+	Mm
		1145464 H2A2C_MOUSE (1-122): 1.62e-61: 185: 89.43		EED_MOUSE (202-423): 2.51e-09: 60.7: 8.33
+	Hs
		267858 H2A1_HUMAN (1-122): 3.27e-61: 185: 89.43		EED_HUMAN (202-423): 2.51e-09: 60.7: 8.33
+	Mm
		83336 H2A1B_MOUSE (1-122): 3.57e-61: 185: 88.62		EED_MOUSE (202-423): 2.51e-09: 60.7: 8.33