HitPredict

Interactor 1: ARF1 (P84077)
ADP-ribosylation factor 1 (EC 3.6.5.2)
Gene: ARF1

Interactor 2: CYH2 (Q99418)
Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)
Gene: CYTH2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.885

The method score is based on:

Property Details
Experiments 9417041, 17563369, 10198630, 14654833
Identification Methods enzymatic study, classical fluorescence spectroscopy, biochemical, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Arf~PH, Arf~Sec7
Common GO terms GO:0000139 - Golgi membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 181
Hs

1 400
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Sc
+ Sc
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024