HitPredict

Interactor 1: ARF1 (P84077)
ADP-ribosylation factor 1 (EC 3.6.5.2)
Gene: ARF1

Interactor 2: COPG1 (Q9Y678)
Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP)
Gene: COPG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	10720466
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~Arf
Common GO terms	GO:0000139 - Golgi membrane GO:0005829 - cytosol GO:0006886 - intracellular protein transport
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 181 Hs			1 874
+	Hs
		913217 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		574783 ARF4_HUMAN (1-180): 1.54e-69: 210: 80.56		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		950752 ARF5_HUMAN (1-180): 2.95e-68: 207: 80.56		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		913157 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		574769 ARF4_HUMAN (1-180): 1.54e-69: 210: 80.56		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		950736 ARF5_HUMAN (1-180): 2.95e-68: 207: 80.56		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		897411 ARF3_HUMAN (1-181): 6.38e-68: 206: 96.13		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Dm
		778370 ARF4_DROME (1-180): 1.99e-68: 207: 81.11		COPG_DROME (11-874): 0: 719: 60.28
+	Dm
		897447 ARF1_DROME (1-179): 7.72e-67: 203: 96.65		COPG_DROME (11-874): 0: 719: 60.28
+	Hs
		912875 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		AP1B1_HUMAN (14-872): 0: 650: 13.46
+	Hs
		950481 ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00		AP1B1_HUMAN (14-872): 0: 650: 13.46
+	Dm
		778364 ARF4_DROME (1-180): 1.99e-68: 207: 81.11		Q24253_DROME (14-872): 0: 629: 13.50
+	Dm
		897433 ARF1_DROME (1-179): 7.72e-67: 203: 96.65		Q24253_DROME (14-872): 0: 629: 13.50
+	Hs
		912839 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		AP2B1_HUMAN (14-871): 0: 591: 12.40
+	Hs
		321520 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		AP2A1_HUMAN (24-874): 0: 582: 14.63
+	Hs
		212615 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		AP1G1_HUMAN (17-741): 2.63e-170: 516: 15.52
+	Hs
		212618 ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00		AP1G1_HUMAN (17-741): 2.63e-170: 516: 15.52
+	Sc
		503061 ARF1_YEAST (1-179): 4.31e-65: 199: 77.65		COPG_YEAST (7-873): 7.79e-169: 516: 32.91