HitPredict

Interactor 1: ARF5 (P84085)
ADP-ribosylation factor 5
Gene: ARF5

Interactor 2: SRPRB (Q9Y5M8)
Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1)
Gene: SRPRB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005525 - GTP binding GO:0005794 - Golgi apparatus GO:0006886 - intracellular protein transport GO:0016192 - vesicle-mediated transport
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 180 Hs			1 271
+	Sc
		503036 ARF1_YEAST (1-179): 4.21e-78: 232: 69.83		ARF1_YEAST (46-239): 6.75e-76: 230: 21.65
+	Hs
		912847 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		ARF5_HUMAN (46-240): 5.42e-75: 227: 21.03
+	Hs
		574648 ARF4_HUMAN (1-180): 3.62e-70: 212: 90.00		ARF5_HUMAN (46-240): 5.42e-75: 227: 21.03
+	Hs
		913211 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Sc
		503044 ARF1_YEAST (1-179): 4.21e-78: 232: 69.83		ARF2_YEAST (46-240): 5.76e-63: 197: 21.54
+	Dm
		778363 ARF4_DROME (1-180): 1.02e-77: 231: 83.89		ARF1_DROME (46-239): 1.12e-62: 196: 22.17
+	Hs
		912837 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		RAB1A_HUMAN (54-265): 1.14e-63: 200: 14.49
+	Hs
		574643 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		ARF4_HUMAN (46-240): 2.72e-63: 198: 20.51
+	Hs
		912846 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		ARF1_HUMAN (46-240): 2.73e-62: 195: 21.54
+	Zm
		73944 B4FAE1_MAIZE (5-180): 1.19e-69: 211: 19.34		B4FAE1_MAIZE (57-268): 6.81e-65: 203: 12.84
+	Zm
		21601 A0A1D6HW42_MAIZE (1-180): 7.87e-69: 209: 80.56		A0A1D6HW42_MAIZE (46-240): 4.09e-65: 203: 22.56
+	Hs
		574638 ARF4_HUMAN (1-180): 3.62e-70: 212: 90.00		ARF3_HUMAN (46-240): 1.64e-62: 196: 22.05
+	Hs
		574647 ARF4_HUMAN (1-180): 3.62e-70: 212: 90.00		ARF1_HUMAN (46-240): 2.73e-62: 195: 21.54
+	Hs
		897350 ARF5_HUMAN (1-180): 1.69e-69: 210: 100.00		ARF3_HUMAN (46-240): 1.64e-62: 196: 22.05
+	Hs
		950474 ARF5_HUMAN (1-180): 1.69e-69: 210: 100.00		ARF1_HUMAN (46-240): 2.73e-62: 195: 21.54
+	Hs
		881497 ARF5_HUMAN (1-180): 1.69e-69: 210: 100.00		ARL4C_HUMAN (67-197): 1.37e-11: 64: 25.56