HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: RBM19 (Q9Y4C8)
Probable RNA-binding protein 19 (RNA-binding motif protein 19)
Gene: RBM19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 164 Hs			1 960
+	Hs
		1028887 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		RBM19_HUMAN (1-960): 1.48e-162: 503: 100.00
+	Hs
		853881 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		PABP4_HUMAN (2-283): 1.29e-26: 118: 13.48
+	Hs
		516466 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PABP1_HUMAN (3-272): 7.27e-19: 93.7: 11.85
+	Hs
		516478 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		PABP1_HUMAN (3-272): 7.27e-19: 93.7: 11.85
+	Hs
		266904 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		PABP1_HUMAN (3-272): 7.27e-19: 93.7: 11.85
+	Hs
		516425 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		PABP1_HUMAN (3-272): 7.27e-19: 93.7: 11.85
+	Hs
		516495 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		PABP1_HUMAN (3-272): 7.27e-19: 93.7: 11.85
+	Hs
		474017 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PAB4L_HUMAN (3-80): 2.51e-16: 84.1: 25.64
+	Hs
		516339 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		PABP1_HUMAN (3-272): 7.27e-19: 93.7: 11.85
+	Hs
		992875 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		PABP5_HUMAN (3-119): 4.94e-14: 77.1: 19.66
+	Hs
		474021 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		PAB4L_HUMAN (3-80): 2.51e-16: 84.1: 25.64
+	Hs
		267046 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		PABP5_HUMAN (3-119): 4.94e-14: 77.1: 19.66
+	Hs
		951937 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		ELAV2_HUMAN (732-894): 1.61e-11: 68.9: 28.83
+	Hs
		992743 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		ELAV2_HUMAN (732-894): 1.61e-11: 68.9: 28.83
+	Hs
		1119141 PAP1L_HUMAN (1-94): 4.25e-21: 90.7: 22.55		PABP5_HUMAN (3-119): 4.94e-14: 77.1: 19.66
+	Hs
		266989 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		HNRPD_HUMAN (699-900): 4.2e-12: 70.9: 29.70
+	Hs
		682741 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		HNRH1_HUMAN (296-459): 5.02e-12: 71.2: 31.95
+	Hs
		853888 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		HNRPD_HUMAN (699-900): 4.2e-12: 70.9: 29.70
+	Hs
		266976 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		ELAV2_HUMAN (732-894): 1.61e-11: 68.9: 28.83
+	Hs
		1020249 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		ELAV2_HUMAN (732-894): 1.61e-11: 68.9: 28.83