Protein: AKL1
Serine/threonine-protein kinase AKL1 (EC 2.7.11.1)

Gene: AKL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 144
UniProt ID: P38080

Gene Ontology (top 5):
GO:0000147 - actin cortical patch assembly
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005628 - prospore membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

392593

HSP82
ATP-dependent molecular chaperone HSP82

3

18

High-throughput

0.827

High

757693

EDE1
EH domain-containing and endocytosis protein 1

2

16

High-throughput

0.799

High

793185

FPK1
Flippase kinase 1

2

12

Small-scale

0.778

High

509890

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

2

8

High-throughput

0.768

High

793155

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

2

6

High-throughput

0.762

High

793143

AKL1
Serine/threonine-protein kinase AKL1

1

18

High-throughput

0.698

High

709711

BMH1
Protein BMH1

4

20

High-throughput

0.694

High

622932

CSK22
Casein kinase II subunit alpha'

1

12

High-throughput

0.691

High

665812

KPC1
Protein kinase C-like 1

1

8

High-throughput

0.691

High

692339

KCC1
Calcium/calmodulin-dependent protein kinase I

1

13

High-throughput

0.691

High

793160

PRK1
Actin-regulating kinase PRK1

1

17

High-throughput

0.691

High

793188

ARK1
Actin-regulating kinase 1

1

18

High-throughput

0.691

High

793196

SKI8
Antiviral protein SKI8

3

1

High-throughput

0.672

High

437914

KAPC
cAMP-dependent protein kinase type 3

1

14

High-throughput

0.647

High

441354

KAPB
cAMP-dependent protein kinase type 2

1

13

High-throughput

0.647

High

445334

CDC31
Cell division control protein 31

1

14

High-throughput

0.647

High

793146

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

17

High-throughput

0.647

High

793147

MIP6
RNA-binding protein MIP6

1

3

High-throughput

0.647

High

793171

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

17

High-throughput

0.647

High

793186

JJJ1
J protein JJJ1

1

5

High-throughput

0.647

High

793187

CRZ1
Transcriptional regulator CRZ1

1

1

High-throughput

0.647

High

793200

VHS1
Serine/threonine-protein kinase VHS1

1

19

High-throughput

0.647

High

737831

HOG1
Mitogen-activated protein kinase HOG1

1

16

Small-scale

0.621

High

744831

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

2

10

Small-scale

0.619

High

454728

KAPR
cAMP-dependent protein kinase regulatory subunit

1

5

High-throughput

0.618

High

509508

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

13

High-throughput

0.618

High

579241

HSC82
ATP-dependent molecular chaperone HSC82

1

18

High-throughput

0.618

High

600678

SEC2
Rab guanine nucleotide exchange factor SEC2

2

2

High-throughput

0.602

High

793149

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

High-throughput

0.586

High

394472

EF1A
Elongation factor 1-alpha

2

2

High-throughput

0.584

High

523688

HSP71
Heat shock protein SSA1

2

13

High-throughput

0.584

High

673464

RHEB
GTP-binding protein RHB1

1

9

High-throughput

0.579

High

692559

NSR1
Nuclear localization sequence-binding protein

1

2

High-throughput

0.579

High

737400

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

3

High-throughput

0.575

High

793152

SET5
Histone-lysine N-methyltransferase SET5

2

0

Small-scale

0.569

High

526469

HSP72
Heat shock protein SSA2

2

13

High-throughput

0.552

High

544565

SSB1
Ribosome-associated molecular chaperone SSB1

2

15

High-throughput

0.552

High

672400

STE50
Protein STE50

2

0

High-throughput

0.551

High

721865

XPO1
Exportin-1

1

6

High-throughput

0.536

High

739065

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

9

High-throughput

0.536

High

751847

SLA2
Protein SLA2

1

13

High-throughput

0.536

High

793162

DSN1
Kinetochore-associated protein DSN1

2

2

High-throughput

0.533

High

793174

TRM9
tRNA

1

0

High-throughput

0.518

High

454161

SYH
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

366048

CBPY
Carboxypeptidase Y

1

2

High-throughput

0.501

High

438673

SC160
Protein SCP160

1

3

High-throughput

0.501

High

504590

YH11A
Transposon Ty1-H Gag polyprotein

1

2

High-throughput

0.501

High

585612

STI1
Heat shock protein STI1

1

5

High-throughput

0.501

High

598849

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.501

High

692501

GYS2
Glycogen [starch] synthase isoform 2

1

2

High-throughput

0.501

High

741409

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.501

High

782299

RNZ
Ribonuclease Z

1

1

High-throughput

0.501

High

793150

AP18A
Clathrin coat assembly protein AP180A

1

12

High-throughput

0.501

High

793153

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.501

High

793164

MVP1
Sorting nexin MVP1

1

2

High-throughput

0.501

High

793167

LSB3
LAS seventeen-binding protein 3

1

9

High-throughput

0.501

High

793170

ALY2
Arrestin-related trafficking adapter 3

1

3

High-throughput

0.501

High

793175

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

High-throughput

0.501

High

793203

YM54
Uncharacterized protein YMR196W

1

1

High-throughput

0.501

High

793205

DCE
Glutamate decarboxylase

1

1

High-throughput

0.501

High

793208

ENT2
Epsin-2

1

5

High-throughput

0.501

High

793163

SA185
SIT4-associating protein SAP185

1

3

High-throughput

0.489

High

793151

KOG1
Target of rapamycin complex 1 subunit KOG1

1

4

High-throughput

0.481

High

416224

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.480

High

439576

LEU1
2-isopropylmalate synthase

1

0

High-throughput

0.480

High

452500

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.480

High

455614

TRPD
Anthranilate phosphoribosyltransferase

1

0

High-throughput

0.480

High

470188

MET2
Homoserine O-acetyltransferase

1

0

High-throughput

0.480

High

616097

ART10
Arrestin-related trafficking adapter 10

1

0

High-throughput

0.480

High

757810

YBF5
Deoxyribonuclease Tat-D

1

0

High-throughput

0.480

High

793148

PANE
2-dehydropantoate 2-reductase

1

0

High-throughput

0.480

High

793157

SYPM
Probable proline--tRNA ligase, mitochondrial

1

0

High-throughput

0.480

High

793166

ATG18
Autophagy-related protein 18

1

0

High-throughput

0.480

High

793169

ARC1
tRNA-aminoacylation cofactor ARC1

1

0

High-throughput

0.480

High

793181

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.480

High

793199

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.480

High

793204

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.480

High

793207

FSH2
Family of serine hydrolases 2

1

0

High-throughput

0.480

High

793209

DBP9
ATP-dependent RNA helicase DBP9

1

0

High-throughput

0.480

High

793212

AB140
tRNA(Thr)

1

0

High-throughput

0.480

High

793214

GRE1
Protein GRE1

1

0

High-throughput

0.480

High

793216

RIB2
Bifunctional protein RIB2 [Includes: tRNA pseudouridine(32) synthase, cytoplasmic

1

0

High-throughput

0.480

High

479677

F16P
Fructose-1,6-bisphosphatase

1

1

Small-scale

0.479

High

679591

CDC48
Cell division control protein 48

1

6

High-throughput

0.479

High

760240

BMH2
Protein BMH2

1

20

High-throughput

0.479

High

762900

CYPD
Peptidyl-prolyl cis-trans isomerase D

1

1

High-throughput

0.479

High

793145

ATG8
Autophagy-related protein 8

1

4

High-throughput

0.479

High

793217

CMR1
DNA damage-binding protein CMR1

1

4

High-throughput

0.479

High

793184

HST1
NAD-dependent protein deacetylase HST1

1

2

High-throughput

0.470

High

670251

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.458

High

781504

YKR18
IML2-like protein YKR018C

1

0

High-throughput

0.458

High

793173

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

793189

UBX4
UBX domain-containing protein 4

1

0

High-throughput

0.458

High

793198

NAB6
RNA-binding protein NAB6

1

0

High-throughput

0.458

High

793201

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

661398

PSA3
Proteasome subunit alpha type-3

1

4

High-throughput

0.457

High

697763

THIK
3-ketoacyl-CoA thiolase, peroxisomal

1

1

High-throughput

0.457

High

739607

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.457

High

740717

SRP40
Suppressor protein SRP40

1

2

High-throughput

0.457

High

760550

SCD5
Protein SCD5

1

1

High-throughput

0.457

High

793154

RS26B
Small ribosomal subunit protein eS26B

1

1

High-throughput

0.457

High

793161

UTP25
U3 small nucleolar RNA-associated protein 25

1

2

High-throughput

0.457

High

793177

MALX3
Oligo-1,6-glucosidase IMA1

1

2

High-throughput

0.457

High

793180

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.457

High

793183

6PGD2
6-phosphogluconate dehydrogenase, decarboxylating 2

1

1

High-throughput

0.457

High

793193

NUP49
Nucleoporin NUP49/NSP49

1

3

High-throughput

0.457

High

793206

IVY1
Protein IVY1

1

1

High-throughput

0.457

High

793211

VHS3
Phosphopantothenoylcysteine decarboxylase subunit VHS3

1

2

High-throughput

0.457

High

453550

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

510420

HSP77
Import motor subunit, mitochondrial

1

15

High-throughput

0.445

High

575929

CYPH
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.445

High

684694

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.445

High

793158

SSB2
Ribosome-associated molecular chaperone SSB2

1

15

High-throughput

0.445

High

793159

6P21
6-phosphofructo-2-kinase 1

1

2

High-throughput

0.445

High

793179

HOS2
Probable histone deacetylase HOS2

1

6

High-throughput

0.445

High

360970

CCPR
Cytochrome c peroxidase, mitochondrial

1

2

High-throughput

0.437

High

382044

H4
Histone H4

1

1

High-throughput

0.437

High

479977

PRTB
Cerevisin

1

2

High-throughput

0.437

High

594328

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.437

High

706864

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

792770

ANM1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.437

High

793156

GDI1
Rab GDP-dissociation inhibitor

1

1

High-throughput

0.437

High

793165

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

7

High-throughput

0.437

High

793176

SAP4
SIT4-associating protein SAP4

1

3

High-throughput

0.437

High

793190

H3
Histone H3

1

5

High-throughput

0.437

High

793192

NUM1
Nuclear migration protein NUM1

1

19

High-throughput

0.437

High

793168

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.407

High

793210

BRE1
E3 ubiquitin-protein ligase BRE1

1

9

High-throughput

0.407

High

793197

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.298

High

678317

RSC6
Chromatin structure-remodeling complex protein RSC6

1

0

High-throughput

0.261

Low

793172

PXP2
Peroxisomal protein 2

1

0

High-throughput

0.261

Low

793182

YG1D
Probable transcriptional regulatory protein HAH1

1

0

High-throughput

0.261

Low

793194

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.261

Low

793195

FOX2
Peroxisomal hydratase-dehydrogenase-epimerase

1

0

High-throughput

0.261

Low

793215

SSF2
Ribosome biogenesis protein SSF2

1

0

High-throughput

0.261

Low

763516

MAC1
Metal-binding activator 1

1

0

High-throughput

0.249

Low

764056

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

793030

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

793144

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

793178

COG1
Conserved oligomeric Golgi complex subunit 1

1

0

High-throughput

0.249

Low

793202

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

793213

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.249

Low

793191

YD413
Putative uncharacterized protein YDR413C

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025