HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: RBM8A (Q9Y5S9)
RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A)
Gene: RBM8A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	23084401
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006406 - mRNA export from nucleus and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 164 Hs			1 174
+	Hs
		993014 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		RBM8A_HUMAN (1-169): 1.46e-41: 138: 100.00
+	Hs
		703438 CSTF2_HUMAN (10-110): 1.87e-25: 103: 25.47		CSTFT_HUMAN (63-162): 1.63e-29: 115: 34.00
+	Hs
		951977 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		SF3B4_HUMAN (67-149): 3.35e-25: 101: 28.92
+	Hs
		516466 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		516478 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Zm
		30171 A0A1D6M1U3_MAIZE (5-85): 1.01e-30: 115: 42.17		A0A1D6K4S7_MAIZE (62-153): 3.18e-18: 82.5: 29.35
+	Hs
		266904 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		516425 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		PABP1_HUMAN (64-158): 1.19e-23: 98.4: 23.16
+	Hs
		1054347 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		1084450 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		PPIE_HUMAN (74-160): 1.75e-17: 79.4: 31.03
+	Hs
		680437 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		TIA1_HUMAN (68-162): 8.55e-20: 86.8: 24.21
+	Mm
		857340 SRSF1_MOUSE (9-80): 1.1e-25: 100: 48.65		TIA1_MOUSE (68-162): 6.72e-20: 86.8: 24.21
+	Hs
		474017 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PAB4L_HUMAN (73-151): 1.5e-18: 83: 26.58
+	Hs
		951964 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		992769 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Mm
		936481 SRSF1_MOUSE (9-80): 1.1e-25: 100: 48.65		TIAR_MOUSE (75-171): 4.23e-17: 79.4: 31.63
+	Hs
		952176 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PPIE_HUMAN (74-160): 1.75e-17: 79.4: 31.03
+	Hs
		266990 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		RBM39_HUMAN (26-172): 5.83e-18: 82.2: 14.97
+	Hs
		1028873 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		PPIE_HUMAN (74-160): 1.75e-17: 79.4: 31.03