HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: CAF1A (Q13111)
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150) (hp150)
Gene: CHAF1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33961781, 36089195, 23075851
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006334 - nucleosome assembly GO:0032991 - protein-containing complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 956
+	Hs
		934715 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		CAF1A_HUMAN (1-956): 0: 589: 100.00
+	Hs
		1024470 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		CAF1A_HUMAN (1-956): 0: 589: 100.00
+	Hs
		1024482 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		CAF1A_HUMAN (1-956): 0: 589: 100.00
+	Hs
		828215 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		CAF1A_HUMAN (1-956): 0: 589: 100.00
+	Mm
		952271 H32_MOUSE (1-136): 5.32e-59: 180: 97.06		CAF1A_MOUSE (1-933): 1.43e-158: 491: 60.47
+	Hs
		934881 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		NIPBL_HUMAN (19-811): 1.39e-68: 253: 11.83
+	Hs
		952407 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		NIPBL_HUMAN (19-811): 1.39e-68: 253: 11.83
+	Hs
		828271 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		NIPBL_HUMAN (19-811): 1.39e-68: 253: 11.83
+	Mm
		356131 H3C_MOUSE (1-136): 4.77e-60: 183: 98.53		TAOK2_MOUSE (171-716): 2.77e-37: 154: 12.88
+	Sc
		704605 H3_YEAST (1-136): 3.62e-54: 168: 90.44		SEC3_YEAST (32-630): 3.06e-36: 151: 13.11
+	Hs
		254470 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ROCK2_HUMAN (143-739): 2.85e-24: 112: 10.98
+	Hs
		935346 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		BAZ2B_HUMAN (290-558): 5.71e-23: 108: 17.80
+	Sc
		704591 CENPA_YEAST (18-134): 3.39e-40: 135: 56.67		SEC3_YEAST (32-630): 3.06e-36: 151: 13.11
+	Sp
		457184 H31_SCHPO (1-136): 1.12e-57: 177: 91.91		RLF2_SCHPO (263-604): 3.13e-23: 107: 22.04
+	Sc
		902158 H3_YEAST (1-136): 3.62e-54: 168: 90.44		RLF2_YEAST (262-645): 1.06e-24: 112: 21.47
+	Hs
		934906 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		WDR87_HUMAN (49-725): 1.77e-12: 74.1: 11.35
+	Sc
		730959 CENPA_YEAST (18-134): 3.39e-40: 135: 56.67		RLF2_YEAST (262-645): 1.06e-24: 112: 21.47
+	Dm
		356125 H3_DROME (1-136): 5.32e-59: 180: 97.06		Q9W3D1_DROME (112-670): 3.78e-10: 66.4: 8.39