HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: CAF1B (Q13112)
Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7)
Gene: CHAF1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27705803, 33961781, 36089195
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 559
+	Hs
		934716 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		CAF1B_HUMAN (1-559): 1.02e-137: 412: 100.00
+	Hs
		1024551 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		CAF1B_HUMAN (1-559): 1.02e-137: 412: 100.00
+	Hs
		1024562 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		CAF1B_HUMAN (1-559): 1.02e-137: 412: 100.00
+	Dm
		53056 H3_DROME (1-136): 5.32e-59: 180: 97.06		A1Z898_DROME (1-547): 1.31e-91: 298: 35.29
+	Hs
		867850 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		HIRA_HUMAN (1-555): 1.22e-86: 290: 21.19
+	Hs
		867853 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		HIRA_HUMAN (1-555): 1.22e-86: 290: 21.19
+	Hs
		867878 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		HIRA_HUMAN (1-555): 1.22e-86: 290: 21.19
+	Mm
		952748 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		HIRA_MOUSE (1-555): 1.56e-84: 284: 22.02
+	Hs
		828179 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		HIRA_HUMAN (1-555): 1.22e-86: 290: 21.19
+	Sc
		690852 H3_YEAST (1-136): 3.62e-54: 168: 90.44		HIR1_YEAST (1-551): 7.27e-75: 255: 22.50
+	Sc
		902046 H3_YEAST (1-136): 3.62e-54: 168: 90.44		CAC2_YEAST (1-435): 7.1e-72: 239: 32.20
+	Hs
		792992 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		LIS1_HUMAN (222-474): 9.92e-34: 134: 8.81
+	At
		886471 H33_ARATH (1-136): 3.83e-60: 183: 95.59		HIRA_ARATH (4-195): 7.34e-25: 111: 15.63
+	Hs
		935208 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		TBL1R_HUMAN (211-422): 1.4e-24: 109: 7.93
+	Hs
		934971 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		DAW1_HUMAN (308-459): 6.78e-22: 100: 9.80
+	Hs
		245614 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		TBL1X_HUMAN (2-97): 2.19e-14: 78.1: 18.75
+	Hs
		903117 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21
+	Sc
		730872 CENPA_YEAST (18-134): 3.39e-40: 135: 56.67		COPA_YEAST (162-426): 2.1e-28: 122: 6.83
+	Hs
		903128 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21
+	Hs
		903260 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21