HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: TAF3 (Q5VWG9)
Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140)
Gene: TAF3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	36089195, 20953165
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 929
+	Hs
		934868 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00
+	Hs
		1086177 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		TAF3_HUMAN (1-914): 6.23e-88: 302: 100.00
+	Hs
		1068543 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		PLEC_HUMAN (30-873): 1.38e-72: 265: 10.21
+	Hs
		934763 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56
+	Hs
		952338 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MDC1_HUMAN (6-886): 7.09e-49: 191: 11.56
+	Hs
		935149 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46
+	Hs
		952572 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		RSF1_HUMAN (161-915): 1.32e-37: 155: 10.46
+	Hs
		935121 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		CHAP1_HUMAN (118-739): 9.43e-30: 128: 11.47
+	Hs
		952550 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		CHAP1_HUMAN (118-739): 9.43e-30: 128: 11.47
+	Hs
		1086277 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		CHAP1_HUMAN (118-739): 9.43e-30: 128: 11.47
+	Hs
		935049 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		TITIN_HUMAN (187-860): 3.72e-13: 76.3: 9.87
+	Hs
		934668 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ANK2_HUMAN (167-801): 1.73e-12: 74.2: 17.53
+	Hs
		152625 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		KMT2D_HUMAN (256-885): 5.06e-11: 69.4: 11.25
+	Hs
		152661 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		KMT2D_HUMAN (256-885): 5.06e-11: 69.4: 11.25
+	Mm
		101827 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		F8WI37_MOUSE (131-864): 3.14e-10: 66.7: 7.94
+	Hs
		934881 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		NIPBL_HUMAN (274-754): 7.04e-10: 65.4: 16.73
+	Hs
		935004 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		KMT2C_HUMAN (147-879): 1.4e-09: 64.4: 8.57
+	Hs
		952407 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		NIPBL_HUMAN (274-754): 7.04e-10: 65.4: 16.73
+	Hs
		952479 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		KMT2C_HUMAN (147-879): 1.4e-09: 64.4: 8.57
+	Hs
		1086228 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		KMT2C_HUMAN (147-879): 1.4e-09: 64.4: 8.57