HitPredict

Interactor 1: CLF1 (P87312)
Pre-mRNA-splicing factor cwf4 (Complexed with cdc5 protein 4)
Gene: cwf4

Interactor 2: BRR2 (Q9UT24)
Pre-mRNA-splicing factor brr2 (EC 3.6.4.13) (Pre-mRNA-splicing factor spp41) (Pre-mRNA-splicing helicase BRR2)
Gene: BRR2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	26682798, 31219728
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 674 Sp			1 2176
+	At
		98519 F4JZX8_ARATH (6-669): 1.77e-117: 369: 48.96		DEXHC_ARATH (17-2165): 0: 1702: 46.03
+	Sp
		1350845 SYF1_SCHPO (26-656): 5.17e-57: 208: 16.67		BRR2_SCHPO (1-2176): 0: 1739: 100.00
+	Hs
		271991 PRP6_HUMAN (326-623): 9.94e-11: 67.3: 14.19		U520_HUMAN (21-2167): 0: 1780: 48.24
+	Sp
		1015544 PRP1_SCHPO (217-662): 6.86e-20: 96.5: 14.20		BRR2_SCHPO (1-2176): 0: 1739: 100.00
+	Dm
		54175 SYF1_DROME (3-590): 3.42e-30: 129: 16.67		U520_DROME (21-2166): 0: 1705: 47.80
+	At
		1338521 Q9LKU3_ARATH (23-580): 5.19e-28: 122: 15.41		DEXHC_ARATH (17-2165): 0: 1702: 46.03
+	Sc
		697276 CLF1_YEAST (12-668): 2.23e-86: 286: 38.74		BRR2_YEAST (19-2165): 0: 1349: 41.32
+	Sc
		586385 PRP6_YEAST (79-364): 1.16e-11: 70.3: 14.92		BRR2_YEAST (19-2165): 0: 1349: 41.32
+	Sc
		697256 SYF1_YEAST (4-321): 5.03e-11: 68: 18.63		BRR2_YEAST (19-2165): 0: 1349: 41.32
+	Sp
		143121 CLF1_SCHPO (1-674): 4.95e-138: 421: 100.00		YE02_SCHPO (388-1013): 1.8e-93: 330: 19.97
+	Sp
		143198 SYF1_SCHPO (26-656): 5.17e-57: 208: 16.67		YE02_SCHPO (388-1013): 1.8e-93: 330: 19.97
+	Hs
		175083 OGT1_HUMAN (4-260): 3.19e-31: 132: 9.69		DDX17_HUMAN (1279-1772): 9.55e-100: 341: 11.49
+	Hs
		133770 OGT1_HUMAN (4-260): 3.19e-31: 132: 9.69		DDX3X_HUMAN (1297-1770): 2.99e-98: 334: 12.92
+	Hs
		174608 OGT1_HUMAN (4-260): 3.19e-31: 132: 9.69		DDX5_HUMAN (1278-1767): 3.54e-97: 329: 11.38
+	Sc
		810915 RRP5_YEAST (335-623): 3.08e-18: 91.8: 15.75		MTR4_YEAST (431-1027): 2.92e-99: 349: 18.15
+	Sp
		143158 PRP1_SCHPO (217-662): 6.86e-20: 96.5: 14.20		YE02_SCHPO (388-1013): 1.8e-93: 330: 19.97
+	Hs
		300219 PRP6_HUMAN (326-623): 9.94e-11: 67.3: 14.19		DDX17_HUMAN (1279-1772): 9.55e-100: 341: 11.49
+	Hs
		1058019 RRP5_HUMAN (9-277): 5.49e-17: 87.6: 16.03		DDX23_HUMAN (1271-1785): 6.11e-77: 276: 12.75
+	Hs
		1160966 CTR9_HUMAN (228-669): 5.16e-15: 81.2: 14.44		DDX23_HUMAN (1271-1785): 6.11e-77: 276: 12.75
+	Hs
		300254 PRP6_HUMAN (326-623): 9.94e-11: 67.3: 14.19		DDX23_HUMAN (1271-1785): 6.11e-77: 276: 12.75