HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: BRK1 (Q8WUW1)
Protein BRICK1 (BRK1)
Gene: BRK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0007015 - actin filament organization GO:0010592 - positive regulation of lamellipodium assembly GO:0030027 - lamellipodium and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 75
+	Hs
		988561 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		BRK1_HUMAN (1-75): 1.6e-36: 119: 100.00
+	Hs
		953585 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		BRK1_HUMAN (1-75): 1.6e-36: 119: 100.00
+	Hs
		955416 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		BRK1_HUMAN (1-75): 1.6e-36: 119: 100.00
+	Hs
		962316 RHOA_HUMAN (5-192): 1.59e-77: 231: 54.26		BRK1_HUMAN (1-75): 1.6e-36: 119: 100.00
+	Hs
		466383 RHOC_HUMAN (5-192): 3.56e-75: 225: 54.79		BRK1_HUMAN (1-75): 1.6e-36: 119: 100.00